Evidence map›Paper›PMID 25018681›Full record

ArticleInternational journal of biomedical science : IJBS2014

A Comparative Study of Serum Uric Acid levels and Lipid Ratios in Coronary Artery Disease Patients.

R Sathiya, V Kuzhandai Velu, G Niranjan, A R Srinivasan, Ganesh B Amirtha, R Ramesh, M Sathish Babu, Subiman Saha

Open access · greenAbstract read
In one paragraph

Article in International journal of biomedical science : IJBS, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.4field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 11 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

R SathiyaDepartment of Biochemistry, Mahatma Gandhi Medical College and Research Institute (SBV), Pillaiyarkuppam, Puducherry, India;
V Kuzhandai VeluDepartment of Biochemistry, Mahatma Gandhi Medical College and Research Institute (SBV), Pillaiyarkuppam, Puducherry, India;
G NiranjanDepartment of Biochemistry, Mahatma Gandhi Medical College and Research Institute (SBV), Pillaiyarkuppam, Puducherry, India;
A R SrinivasanDepartment of Biochemistry, Mahatma Gandhi Medical College and Research Institute (SBV), Pillaiyarkuppam, Puducherry, India;
Ganesh B AmirthaDepartment of Cardiology, Mahatma Gandhi Medical College and Research Institute (SBV), Pillaiyarkuppam, Puducherry, India.
R RameshDepartment of Biochemistry, Mahatma Gandhi Medical College and Research Institute (SBV), Pillaiyarkuppam, Puducherry, India;
M Sathish BabuDepartment of Biochemistry, Mahatma Gandhi Medical College and Research Institute (SBV), Pillaiyarkuppam, Puducherry, India;
Subiman SahaDepartment of Biochemistry, Mahatma Gandhi Medical College and Research Institute (SBV), Pillaiyarkuppam, Puducherry, India;
Mahatma Gandhi Medical College and Research Institute · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionCoronary Artery Disease (CAD) appears to be common in the Indian population of different geographical origins, religions and languages. Measurement of lipid fractions and ratios are widely recommended for risk assessment. A few studies have shown that serum uric acid plays a role in the development of cardiovascular morbidity. Very few reports are cited linking serum uric acid with the lipid fraction in CAD.

objectivesTo find the significance of non-HDL cholesterol, LDL-c/HDL-c ratio, TC/HDL ratio and serum uric acid level in CAD patients. SUBJECTS AND METHODOLOGY: In this study, we included fifty CAD patients as subjects and an equal number of controls. Both subjects and controls were assessed for anthropometric, physiological and biochemical parameters.

resultsThe present study showed significant increased levels of total cholesterol (p=0.002), TAGs (p<0.001), HDL (p=0.005), LDL (p<0.006) and non-HDL cholesterol (p<0.001). LDL-c/HDL-c ratio (p<0.001) and TC/HDL ratio (p<0.001) in CAD patients (subjects) were also significant when compared to controls. Uric acid level in CAD patients was increased (p<0.001).

conclusionSerum Uric Acid, TC/HDL and LDL/HDL ratios could be regarded as objective markers, in association with existing atherogenic dyslipidemia in patients with CAD.

Indexed as

Coronary Artery DiseaseLipid RatioSerum Uric Acid

Identifiers

PMID25018681
PMCPMC4092080
OpenAlexW1750136913

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.