Evidence map›Paper›PMID 25018022›Full record

ReviewVirus research2014

Antiretroviral restriction factors in mice.

Smita Nair, Alan Rein

Abstract readReview
In one paragraph

Review in Virus research, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Deaminase-Dead Mouse APOBEC3 Is anJournal of virology · 2018
    Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Smita NairHIV Drug Resistance Program, Center for Cancer Research, National Cancer Institute, Frederick, MD 21702, USA.
Alan ReinHIV Drug Resistance Program, Center for Cancer Research, National Cancer Institute, Frederick, MD 21702, USA. Electronic address: reina@mail.nih.gov.

Funding

Interactions of APOBEC3 Proteins with Murine Leukemia VirusesZIABC010773 · NCI · DIVISION OF BASIC SCIENCES - NCI · PI REIN, ALAN · 2009 to 2018
$1.9M
Intramural NIH HHS ZIA BC010773
6 · The paper itself

Abstract

One of the most exciting areas in contemporary retrovirus research is the discovery of "restriction factors". These are cellular proteins that act after virus entry to inhibit infection by or replication of retroviruses (and other viruses and intracellular pathogens). We briefly discuss here three antiretroviral restriction factors in mice: Fv1, APOBEC3, and tetherin, touching on both biological and molecular aspects of these restriction systems.

Indexed as

Immunity, InnateAnimalsAntigens, CDBone Marrow Stromal Antigen 2Cytidine DeaminaseHost-Pathogen InteractionsMembrane GlycoproteinsMiceProteinsRetroviridaeRetroviridae InfectionsAntigens, CDApobec3 protein, mouseBone Marrow Stromal Antigen 2BST2 protein, mouseCytidine DeaminaseFv1 protein, mouseMembrane GlycoproteinsProteinsAPOBEC3Fv1 restrictionMurine leukemia virusRetrovirusTetherin

Identifiers

PMID25018022
PMCPMC4254267

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.