ArticleOrganic letters2014
Selenopeptide transamidation and metathesis.
Article in Organic letters, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
8 citing papers in PubMed.
- Selenium in Peptide Chemistry.Molecules (Basel, Switzerland) · 2023Review
- Teaching an Old Compound New Tricks: Reversible Transamidation in Maleamic Acids.Chemistry (Weinheim an der Bergstrasse, Germany) · 2022Article
- Chemical synthesis of human selenoprotein F and elucidation of its thiol-disulfide oxidoreductase activity.Chemical science · 2022Article
- One-Pot Cyclization and Cleavage of Peptides withThe Journal of organic chemistry · 2021Article
- A cysteine selenosulfide redox switch for protein chemical synthesis.Nature communications · 2020Article
- Accelerating chemoselective peptide bond formation using bis(2-selenylethyl)amido peptide selenoester surrogates.Chemical science · 2016Article
- Insights into the deselenization of selenocysteine into alanine and serine.Chemical science · 2015Article
- An Umpolung Approach for the Chemoselective Arylation of Selenocysteine in Unprotected Peptides.Journal of the American Chemical Society · 2015Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Selenopeptides can be transamidated by cysteinyl peptides in water using mild conditions (pH 5.5, 37 °C) in the presence of an arylthiol catalyst. Similar conditions also catalyze the metathesis of selenopeptides. The usefulness of the selenophosphine derived from TCEP (TCEP═Se) for inhibiting the TCEP-induced deselenization of selenocysteine residue is also reported.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.