Evidence map›Paper›PMID 25017682›Full record

ReviewImmunology and allergy clinics of North America2014

Antiviral drug allergy.

Brigitte Milpied-Homsi, Ellen M Moran, Elizabeth J Phillips

Open access · greenAbstract readReview
In one paragraph

Review in Immunology and allergy clinics of North America, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 11 citations in OpenAlex.

  1. Medicinal Fungi with Antiviral Effect.Molecules (Basel, Switzerland) · 2022
    Review
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 3 countries.

Brigitte Milpied-HomsiDepartment of Dermatology, Saint-André Hospital, Bordeaux, WA 6150, France.
Ellen M MoranDivision of infectious diseases, Institute of Immunology and Infectious Disease, Murdoch University, Murdoch, Western Australia.
Elizabeth J PhillipsDivision of infectious diseases, Institute of Immunology and Infectious Disease, Murdoch University, Murdoch, Western Australia; Division of Infectious Diseases, Vanderbilt University Medical Center, 1161 21st Avenue South, A-2200, Medical Center North, Nashville, TN 37232-2582, USA. Electronic address: elizabeth.j.phillips@vanderbilt.edu.
Hôpital Saint-André · FRMurdoch University · AUVanderbilt University Medical Center · US

Funding

The Structural and Functional Basis of HLA-associated Drug HypersensitivityR01AI103348 · NIAID · UNIVERSITY OF FLORIDA · PI OSTROV, DAVID A · 2013 to 2016
$1.5M
NIAID NIH HHS R01 AI103348
6 · The paper itself

Abstract

Antiviral drugs used to treat HIV and hepatitis C are common causes of delayed drug hypersensitivities for which many of the more severe reactions have been recently shown to be immunogenetically mediated such as abacavir hypersensitivity where HLA-B(∗)57:01 is now used routinely as a screening test to exclude patients carrying this allele from abacavir prescription. Most antiviral drug allergies consist of mild to moderate delayed rash without other serious features (eg, fever, mucosal involvement, blistering rash, organ impairment. In these cases treatment can be continued with careful observation and symptomatic management and the discontinuation rate is low.

Indexed as

Antiviral AgentsDisease ManagementDrug HypersensitivityHumansAntiviral AgentsAbacavirAltered peptide repertoireAntiretroviralHuman leukocyte antigenMajor histocompatibility complexNevirapineTelaprevir pharmacogenomics

Identifiers

PMID25017682
PMCPMC4140860
OpenAlexW2068942112

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.