ArticleNature genetics2014
Whole-genome sequencing of 234 bulls facilitates mapping of monogenic and complex traits in cattle.
Article in Nature genetics, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 472 papers, 9 of them syntheses that pooled it.
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Who cites it
472 citing papers in PubMed, 9 syntheses or guidelines pooled it.
- Meta-analysis of six dairy cattle breeds reveals biologically relevant candidate genes for mastitis resistance.Genetics, selection, evolution : GSE · 2024Pooled it
- Sequence-based GWAS meta-analyses for beef production traits.Genetics, selection, evolution : GSE · 2023Pooled it
- X-linked genes influence various complex traits in dairy cattle.BMC genomics · 2023Pooled it
- Integrated analysis of genome-wide association studies and 3D epigenomic characteristics reveal the BMP2 gene regulating loin muscle depth in Yorkshire pigs.PLoS genetics · 2023Pooled it
- Comparison of two multi-trait association testing methods and sequence-based fine mapping of six additive QTL in Swiss Large White pigs.BMC genomics · 2023Pooled it
- GWAS of Reproductive Traits in Large White Pigs on Chip and Imputed Whole-Genome Sequencing Data.International journal of molecular sciences · 2022Pooled it
- GWAS and genomic prediction of milk urea nitrogen in Australian and New Zealand dairy cattle.Genetics, selection, evolution : GSE · 2022Pooled it
- Large-scale association study on daily weight gain in pigs reveals overlap of genetic factors for growth in humans.BMC genomics · 2022Pooled it
- Meta-analysis for milk fat and protein percentage using imputed sequence variant genotypes in 94,321 cattle from eight cattle breeds.Genetics, selection, evolution : GSE · 2020Pooled it
- Resolving Cattle GWAS Loci: Current Progress, Persistent Challenges and Future Directions.Current issues in molecular biology · 2026Review
- Low-Coverage Whole-Genome Resequencing in Livestock and Poultry: Statistical Foundations, Applications and Future Directions.Biology · 2026Review
- Genome-Wide Association Study and Genomic Selection for Average Daily Gain in Ashidan Yak.Animals : an open access journal from MDPI · 2026Article
- Methods to detect selection history in a population under ongoing directional selection.Genetics · 2026Article
- A portable recalibration workflow for reference-based variant calling in non-human genomes.PLoS computational biology · 2026Article
- Inherited Disorders and Disease-Resistance Genomics in Kazakhstan Ruminants: Evidence, Limits and Breeding Priorities.International journal of molecular sciences · 2026Review
- Whole-genome resequencing suggests adaptive role of copy number variation regions in Indian cattle.Tropical animal health and production · 2026Article
- Effect of methylation on genome mutability in cattle.Genetics, selection, evolution : GSE · 2026Article
- An inherited SLC25A12-related recessive form of congenital porencephaly in Limousin cattle.Genetics, selection, evolution : GSE · 2026Article
- Article
- Development and validation of a dual-purpose 60K single nucleotide polymorphism chip for simultaneous genotyping of chicken and duck.Animal bioscience · 2026Article
412 more citing papers are in PubMed but not listed here.
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Authors and funding
30 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The 1000 bull genomes project supports the goal of accelerating the rates of genetic gain in domestic cattle while at the same time considering animal health and welfare by providing the annotated sequence variants and genotypes of key ancestor bulls. In the first phase of the 1000 bull genomes project, we sequenced the whole genomes of 234 cattle to an average of 8.3-fold coverage. This sequencing includes data for 129 individuals from the global Holstein-Friesian population, 43 individuals from the Fleckvieh breed and 15 individuals from the Jersey breed. We identified a total of 28.3 million variants, with an average of 1.44 heterozygous sites per kilobase for each individual. We demonstrate the use of this database in identifying a recessive mutation underlying embryonic death and a dominant mutation underlying lethal chrondrodysplasia. We also performed genome-wide association studies for milk production and curly coat, using imputed sequence variants, and identified variants associated with these traits in cattle.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.