ArticleCell reports2014
Looking under the lamp post: neither fruitless nor doublesex has evolved to generate divergent male courtship in Drosophila.
Article in Cell reports, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
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Who cites it
15 citing papers in PubMed.
- Sex of central neurons controls intestinal niche signalling to drive sex differences in stem cell activity and cancer susceptibility.Nature communications · 2026Article
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- Behavioral Evolution ofGenes · 2020Review
- Phenotypic evolution shaped by current enzyme function in the bioluminescent courtship signals of sea fireflies.Proceedings. Biological sciences · 2019Article
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- Optogenetic Activation of theThe Journal of neuroscience : the official journal of the Society for Neuroscience · 2017Article
- Natural courtship song variation caused by an intronic retroelement in an ion channel gene.Nature · 2016Article
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- Constraints on the evolution of a doublesex target gene arising from doublesex's pleiotropic deployment.Proceedings of the National Academy of Sciences of the United States of America · 2015Article
- Interspecies Gene Transfer as a Method for Understanding the Genetic Basis for Evolutionary Change: Progress, Pitfalls, and Prospects.Frontiers in plant science · 2015Article
- Courtship choreography is stabilized among genetically isolated populations.Behavioral ecology : official journal of the International Society for Behavioral EcologyArticle
- Genome engineering: Drosophila melanogaster and beyond.Wiley interdisciplinary reviews. Developmental biologyReview
Corrections and comments
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Authors and funding
5 authors.
Funding
Abstract
How do evolved genetic changes alter the nervous system to produce different patterns of behavior? We address this question using Drosophila male courtship behavior, which is innate, stereotyped, and evolves rapidly between species. D. melanogaster male courtship requires the male-specific isoforms of two transcription factors, fruitless and doublesex. These genes underlie genetic switches between female and male behaviors, making them excellent candidate genes for courtship behavior evolution. We tested their role in courtship evolution by transferring the entire locus for each gene from divergent species to D. melanogaster. We found that despite differences in Fru+ and Dsx+ cell numbers in wild-type species, cross-species transgenes rescued D. melanogaster courtship behavior and no species-specific behaviors were conferred. Therefore, fru and dsx are not a significant source of evolutionary variation in courtship behavior.
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Registered trials
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