Evidence map›Paper›PMID 25017014›Full record

ArticleThe Angle orthodontist2015

The effect of light-emitting diode and laser on mandibular growth in rats.

Tarek El-Bialy, Adel Alhadlaq, Nayef Felemban, Jasper Yeung, Amal Ebrahim, Ali H Hassan

Erratum issued 6 registry-linked trialsAbstract readComparative Study
In one paragraph

Article in The Angle orthodontist, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. It is linked to 6 registered trials, which are not on this map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02267824 nacompletednot on this map

The Effects of Extraoral Photobiomodulation on the Rate of Orthodontic Alignment

TypeinterventionalSponsorBiolux Research Holdings, Inc.Ran2010 to 2013Enrolled101ConditionsMalocclusionArmsExtraoral OrthoPulse® PBM, Fixed Orthodontic Appliance Treatment
NCT02267837 nacompletednot on this map

OrthoPulse™ and Its Effect on the Rate of Orthodontic Tooth Alignment: A Pilot Feasibility Study.

TypeinterventionalSponsorBiolux Research Holdings, Inc.Ran2012 to 2013Enrolled20ConditionsMalocclusionArmsOrthoPulse™
NCT02267850 nacompletednot on this map

Effect of Intra-Oral Photobiomodulation on Orthodontic Treatment Time: A Randomized Control Trial

TypeinterventionalSponsorBiolux Research Holdings, Inc.Ran2013 to 2016Enrolled29ConditionsMalocclusionArmsFixed Orthodontic Appliance Treatment, OrthoPulse™, Non-Functional OrthoPulse™
NCT02954133 naunknown statusnot on this mapstarted 2016, after this paper: background citation

The Effect of OrthoPulse™ Photobiomodulation on Tooth Movement and Treatment Time When Used With Invisalign Treatment

TypeinterventionalSponsorBiolux Research Holdings, Inc.Ran2016 to 2019Enrolled167ConditionsMalocclusionArmsInvisalign (7 day), Invisalign (5 day), OrthoPulse, Invisalign (3.5 day)
NCT03202355 naterminatednot on this mapstarted 2017, after this paper: background citation

The Effect of OrthoPulse Photobiomodulation on the Rate of Tooth Movement During Alignment With Fixed Appliances

TypeinterventionalSponsorBiolux Research Holdings, Inc.Ran2017 to 2019Enrolled10ConditionsMalocclusionArmsFixed Appliance Orthodontic Treatment, OrthoPulse™
NCT03683017 naunknown statusnot on this mapstarted 2017, after this paper: background citation

OrthoPulse 2.0 and 2.1 Product Evaluation and Assessing Clinical Effectiveness: A Feasibility Study

TypeinterventionalSponsorBiolux Research Holdings, Inc.Ran2017 to 2020Enrolled35ConditionsMalocclusionArmsOrthoPulse 2.0, OrthoPulse 2.1, Invisalign 3.5 Day Wear, Fixed Orthodontic Appliances (Braces)
3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Trial
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Photobiomodulation: lasers vs. light emitting diodes?Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology · 2018
    Article
  9. [Progress in exogenous factors affecting the growth and remodeling of condylar process].Hua xi kou qiang yi xue za zhi = Huaxi kouqiang yixue zazhi = West China journal of stomatology · 2017
    Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors.

Tarek El-Bialya Associate Professor, Department of Orthodontics, School of Dentistry, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, Alberta, Canada.
Adel Alhadlaq
Nayef Felemban
Jasper Yeung
Amal Ebrahim
Ali H Hassan

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo evaluate the effect of a light-emitting diode (LED) and/or low-level laser (LLL) with or without the use of anterior bite jumping appliances (also known as functional appliances [FAs]) on mandibular growth in rats. MATERIALS AND

methodsThirty-six 8-week-old male Sprague-Dawley rats weighing 200 g were obtained from Charles River Canada (St. Constant, QC, Canada) and were divided into six groups of six animals each. Groups were as follows: group 1: LLL; group 2: LLL + FA; group 3: LED; group 4: LED + FA; group 5: FA; and group 6: control (no treatment). Mandibular growth was evaluated by histomorphometric and micro computed tomographic (microCT) analyses.

resultsThe LED and LED + FA groups showed an increase in all condylar tissue parameters compared with other groups.

conclusionThe LED-treated groups showed more mandibular growth stimulation compared with the laser groups.

Indexed as

Orthodontic Appliances, FunctionalAnimalsCartilage, ArticularChondrocytesFibrocartilageLow-Level Light TherapyMaleMandibleMandibular CondyleRatsRats, Sprague-DawleyX-Ray MicrotomographyFunctional applianceLaserLEDMandibular growth

Identifiers

PMID25017014
PMCPMC8631884

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.