Trial reportAmerican journal of epidemiology2014
Simultaneous association of total energy consumption and activity-related energy expenditure with risks of cardiovascular disease, cancer, and diabetes among postmenopausal women.
Trial report in American journal of epidemiology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
42 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Prediction of activity-related energy expenditure using accelerometer-derived physical activity under free-living conditions: a systematic review.International journal of obesity (2005) · 2016Pooled it
- Application of a New Statistical Model for Measurement Error to the Evaluation of Dietary Self-report Instruments.Epidemiology (Cambridge, Mass.) · 2015Pooled it
- Associations of Biomarker-Calibrated Healthy Eating Index-2010 Scores with Chronic Disease Risk and Their Dependency on Energy Intake and Body Mass Index in Postmenopausal Women.The Journal of nutrition · 2023Trial
- Biomarker-Calibrated Macronutrient Intake and Chronic Disease Risk among Postmenopausal Women.The Journal of nutrition · 2021Trial
- Low-Fat Dietary Pattern among Postmenopausal Women Influences Long-Term Cancer, Cardiovascular Disease, and Diabetes Outcomes.The Journal of nutrition · 2019Trial
- Application of blood concentration biomarkers in nutritional epidemiology: example of carotenoid and tocopherol intake in relation to chronic disease risk.The American journal of clinical nutrition · 2019Trial
- Dietary biomarker evaluation in a controlled feeding study in women from the Women's Health Initiative cohort.The American journal of clinical nutrition · 2017Trial
- Trends in body mass index and energy intake with and without biomarker calibration in the USA and Japanese National Nutrition Surveys.Journal of nutritional science · 2026Article
- The impact of exercise on women's health: A bibliometric and visualization analysis (2010-2024).Medicine · 2025Article
- Relevance of Cardiovascular Exercise in Cancer and Cancer Therapy-Related Cardiac Dysfunction.Current heart failure reports · 2024Review
- USING SIMULTANEOUS REGRESSION CALIBRATION TO STUDY THE EFFECT OF MULTIPLE ERROR-PRONE EXPOSURES ON DISEASE RISK UTILIZING BIOMARKERS DEVELOPED FROM A CONTROLLED FEEDING STUDY.The annals of applied statistics · 2024Article
- Physiopathology and Treatment of Obesity and Overweight: A Proposal for a New Anorectic.Journal of obesity · 2024Review
- Association between doubly labelled water-calibrated energy intake and objectively measured physical activity with mortality risk in older adults.The international journal of behavioral nutrition and physical activity · 2023Article
- A Combination Study of Pre- and Clinical Trial: Seaweed Consumption Reduces Aging-Associated Muscle Loss!Aging and disease · 2023Article
- Total energy expenditure as assessed by doubly labeled water and all-cause mortality in a cohort of postmenopausal women.The American journal of clinical nutrition · 2023Article
- Enhancing Capacity for Food and Nutrient Intake Assessment in Population Sciences Research.Annual review of public health · 2023Review
- Using Controlled Feeding Study for Biomarker Development in Regression Calibration for Disease Association Estimation.Statistics in biosciences · 2023Article
- Doubly labelled water-calibrated energy intake associations with mortality risk among older adults.Journal of cachexia, sarcopenia and muscle · 2023Article
- Regression calibration utilizing biomarkers developed from high-dimensional metabolites.Frontiers in nutrition · 2023Article
- Contributions of the Women's Health Initiative to Cardiovascular Research: JACC State-of-the-Art Review.Journal of the American College of Cardiology · 2022Review
Corrections and comments
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Authors and funding
13 authors.
Funding
Abstract
Total energy consumption and activity-related energy expenditure (AREE) estimates that have been calibrated using biomarkers to correct for measurement error were simultaneously associated with the risks of cardiovascular disease, cancer, and diabetes among postmenopausal women who were enrolled in the Women's Health Initiative at 40 US clinical centers and followed from 1994 to the present. Calibrated energy consumption was found to be positively related, and AREE inversely related, to the risks of various cardiovascular diseases, cancers, and diabetes. These associations were not evident in most corresponding analyses that did not correct for measurement error. However, an important analytical caveat relates to the role of body mass index (BMI) (weight (kg)/height (m)(2)). In the calibrated variable analyses, BMI was regarded, along with self-reported data, as a source of information on energy consumption and physical activity, and BMI was otherwise excluded from the disease risk models. This approach cannot be fully justified with available data, and the analyses herein imply a need for improved dietary and physical activity assessment methods and for longitudinal self-reported and biomarker data to test and relax modeling assumptions. Estimated hazard ratios for 20% increases in total energy consumption and AREE, respectively, were as follows: 1.49 (95% confidence interval: 1.18, 1.88) and 0.80 (95% confidence interval: 0.69, 0.92) for total cardiovascular disease; 1.43 (95% confidence interval: 1.17, 1.73) and 0.84 (95% confidence interval: 0.73, 0.96) for total invasive cancer; and 4.17 (95% confidence interval: 2.68, 6.49) and 0.60 (95% confidence interval: 0.44, 0.83) for diabetes.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.