ArticleActa biomaterialia2014
Characterization of living skin using multi-view stereo and isogeometric analysis.
Article in Acta biomaterialia, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
19 citing papers in PubMed, 46 citations in OpenAlex.
- Predictive Modeling of Human Skin Deformation and Growth During Tissue Expansion in Postmastectomy Breast Reconstruction.Journal of biomechanical engineering · 2025Article
- Development and calibration of digital twins for human skin growth in tissue expansion.Acta biomaterialia · 2025Article
- Tissue expansion mitigates radiation-induced skin fibrosis in a porcine model.Acta biomaterialia · 2024Article
- Current progress toward isogeometric modeling of the heart biophysics.Biophysics reviews · 2023Review
- Review
- Multilayer In Vitro Human Skin Tissue Platforms for Quantitative Burn Injury Investigation.Bioengineering (Basel, Switzerland) · 2023Article
- Multi-Fidelity Gaussian Process Surrogate Modeling of Pediatric Tissue Expansion.Journal of biomechanical engineering · 2022Article
- Biological Cover Mitigates Disruption of the Dermal Structure in Mechanically Expanded Skin in a Porcine Model.International journal of molecular sciences · 2022Article
- Data-driven Modeling of the Mechanical Behavior of Anisotropic Soft Biological Tissue.Engineering with computers · 2022Article
- Bayesian calibration of a computational model of tissue expansion based on a porcine animal model.Acta biomaterialia · 2022Article
- Personalized Computational Models of Tissue-Rearrangement in the Scalp Predict the Mechanical Stress Signature of Rotation Flaps.The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association · 2021Article
- Propagation of uncertainty in the mechanical and biological response of growing tissues using multi-fidelity Gaussian process regression.Computer methods in applied mechanics and engineering · 2020Article
- Growth and remodelling of living tissues: perspectives, challenges and opportunities.Journal of the Royal Society, Interface · 2019Review
- Mathematical and computational modelling of skin biophysics: a review.Proceedings. Mathematical, physical, and engineering sciences · 2017Review
- Quantification of Strain in a Porcine Model of Skin Expansion Using Multi-View Stereo and Isogeometric Kinematics.Journal of visualized experiments : JoVE · 2017Article
- The Incompatibility of Living Systems: Characterizing Growth-Induced Incompatibilities in Expanded Skin.Annals of biomedical engineering · 2016Article
- Multi-view stereo analysis reveals anisotropy of prestrain, deformation, and growth in living skin.Biomechanics and modeling in mechanobiology · 2015Article
- Isogeometric Kirchhoff-Love shell formulations for biological membranes.Computer methods in applied mechanics and engineering · 2015Article
- Computational modeling of skin: Using stress profiles as predictor for tissue necrosis in reconstructive surgery.Computers & structures · 2014Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 3 institutions in 1 country.
Funding
Abstract
Skin is our interface with the outside world. In its natural environment, it displays unique mechanical characteristics, such as prestretch and growth. While there is a general agreement on the physiological importance of these features, they remain poorly characterized, mainly because they are difficult to access with standard laboratory techniques. Here we present a new, inexpensive technique to characterize living skin using multi-view stereo and isogeometric analysis. Based on easy-to-create hand-held camera images, we quantify prestretch, deformation and growth in a controlled porcine model of chronic skin expansion. Over a period of 5 weeks, we gradually inflate an implanted tissue expander, take weekly photographs of the experimental scene, reconstruct the geometry from a tattooed surface grid and create parametric representations of the skin surface. After 5 weeks of expansion, our method reveals an average area prestretch of 1.44, an average area stretch of 1.87 and an average area growth of 2.25. Area prestretch is maximal in the ventral region with a value of 2.37, whereas area stretch and area growth are maximal above the center of the expander, with values of 4.05 and 4.81, respectively. Our study has immediate impact on understanding living skin to optimize treatment planning and decision making in plastic and reconstructive surgery. Beyond these direct implications, our experimental design has broad applications in clinical research and basic sciences: it serves as a simple, robust, low cost, easy-to-use tool to reconstruct living membranes, which are difficult to characterize in a conventional laboratory setup.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.