ArticleEnvironmental science and pollution research international2015
Polycyclic aromatic hydrocarbon (PAH) exposure and oxidative stress for a rural population from the North China Plain.
Article in Environmental science and pollution research international, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.
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Who cites it
19 citing papers in PubMed, 1 synthesis or guideline pooled it, 65 citations in OpenAlex.
- Health consequences of exposure to e-waste: an updated systematic review.The Lancet. Planetary health · 2021Pooled it
- Brief exposure to Swedish snus causes divergent vascular responses in healthy male and female volunteers.PloS one · 2018Trial
- Benzo[a]pyrene exposure affect the formation of dental hard tissue via the regulation of glycerophospholipid metabolism.BMC oral health · 2026Article
- Effects of Fish Oil Replacement With Degossypolized Cottonseed Oil on Growth Performance, Proximate Composition, Lipid Metabolism, and Liver Function of Large Yellow Croaker (Aquaculture nutrition · 2025Article
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- IMPACT OF REAL-LIFE ENVIRONMENTAL EXPOSURES ON REPRODUCTION: Evidence for reproductive health effects following exposure to hydraulic fracturing chemical mixtures.Reproduction (Cambridge, England) · 2024Review
- Urinary polycyclic aromatic hydrocarbon metabolites and hyperlipidemia: NHANES 2007-2016.Lipids in health and disease · 2024Article
- Association of mixed polycyclic aromatic hydrocarbons exposure with oxidative stress in Korean adults.Scientific reports · 2024Article
- Differential Occupational Health Risks between Methylated PAHs and PAHs: Monitoring 126 PAHs and 6 Oxidative Stress Markers in Paired Serum-Urine Samples.Environment & health (Washington, D.C.) · 2024Article
- Non-carcinogenic and cumulative risk assessment of exposure of kitchen workers in restaurants and local residents in the vicinity of polycyclic aromatic hydrocarbons.Scientific reports · 2023Article
- Urinary Polycyclic Aromatic Hydrocarbons in a Longitudinal Cohort of Children with CKD: A Case of Reverse Causation?Kidney360 · 2022Article
- Health consequences of disinfection against SARS-CoV-2: Exploring oxidative stress damage using a biomonitoring approach.The Science of the total environment · 2022Article
- Variability in urinary biomarkers of human exposure to polycyclic aromatic hydrocarbons and its association with oxidative stress.Environment international · 2021Article
- Benchmark dose estimation for coke oven emissions based on oxidative damage in Chinese exposed workers.Ecotoxicology and environmental safety · 2020Article
- Urinary metabolites of polycyclic aromatic hydrocarbons in pregnant women and their association with a biomarker of oxidative stress.Environmental science and pollution research international · 2019Article
- Urinary Polycyclic Aromatic Hydrocarbon Metabolite Associations with Biomarkers of Inflammation, Angiogenesis, and Oxidative Stress in Pregnant Women.Environmental science & technology · 2017Article
- High efficiency cabin air filter in vehicles reduces drivers' roadway particulate matter exposures and associated lipid peroxidation.PloS one · 2017Article
- Urinary Metabolites of Polycyclic Aromatic Hydrocarbons and the Association with Lipid Peroxidation: A Biomarker-Based Study between Los Angeles and Beijing.Environmental science & technology · 2016Article
- Monitoring exposure to polycyclic aromatic hydrocarbons in an Australian population using pooled urine samples.Environment international · 2016Article
Corrections and comments
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Authors and funding
6 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Polycyclic aromatic hydrocarbons (PAHs) belong to a class of ubiquitous pollutants and are possibly associated with adverse health effects. In this study, we aimed to assess PAH exposure by measuring the hydroxylated metabolites (hydroxy-PAHs) in urine samples of a rural population from the North China Plain and to explore the possible associations between PAH exposure and oxidative stress indicated by urinary malondialdehyde (MDA) and 8-hydroxy-2′-deoxyguanosine (8-OHdG). High levels of urinary hydroxy-PAHs were observed, with the geometric mean concentrations of 0.57, 2.2, 5.0, 7.0, and 16.6 μg g−1 creatinine for 1-hydroxypyrene, hydroxyphenanthrenes, hydroxyfluorenes, hydroxybiphenyls, and hydroxynaphthalenes, respectively. Particularly in the winter season, the exposures were 2.3–6.0-fold of those in the spring. Corresponding to PAH exposure, levels of urinary MDA were positively associated with hydroxy-PAHs after controlling for confounders in the linear regression models (p < 0.05). An estimation indicated 21.3–39.3 % increment of urinary MDA per one-fold increase of hydroxy-PAHs. In contrast, no significant correlation was found between urinary 8-OHdG and hydroxy-PAHs; alternatively, living at the e-waste recycling site was found a significant factor on this oxidative DNA damage. These results provide evidence on high PAH exposure and the induction of oxidative stress on lipid peroxidation for this rural population.
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