Evidence map›Paper›PMID 25015578›Full record

ArticleThe Journal of pediatrics2014

Variation in the management of infants hospitalized for bronchiolitis persists after the 2006 American Academy of Pediatrics bronchiolitis guidelines.

Todd A Florin, Terri Byczkowski, Richard M Ruddy, Joseph J Zorc, Matthew Test, Samir S Shah

Registry-linked trialOpen access · greenAbstract readMulticenter Study
In one paragraph

Article in The Journal of pediatrics, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03280732 (Lung Ultrasound in Diagnosing and Monitoring of Pulmonary Complications in Children With Acute Bronchiolitis), which is not on this map. Cited by 46 papers.

0numbers the graph read from it
0cells of the map it votes in
46citing papers in PubMed
5.4field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03280732 nacompletednot on this mapstarted 2016, after this paper: background citation

Lung Ultrasound in Diagnosing and Monitoring of Pulmonary Complications in Children With Acute Bronchiolitis

TypeinterventionalSponsorIRCCS Azienda Ospedaliero-Universitaria di BolognaRan2016 to 2018Enrolled87ConditionsBronchiolitis AcuteArmsLung Ultrasound
3 · Its place in the literature

Who cites it

46 citing papers in PubMed, 132 citations in OpenAlex.

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  11. Factors associated with mild bronchiolitis in young infants.Journal of the American College of Emergency Physicians open · 2023
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Todd A FlorinDivision of Emergency Medicine, Cincinnati Children's Hospital Medical Center, Cincinnati, OH; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH. Electronic address: Todd.Florin@cchmc.org.
Terri ByczkowskiDivision of Emergency Medicine, Cincinnati Children's Hospital Medical Center, Cincinnati, OH; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH.
Richard M RuddyDivision of Emergency Medicine, Cincinnati Children's Hospital Medical Center, Cincinnati, OH; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH.
Joseph J ZorcDivision of Emergency Medicine, the Children's Hospital of Philadelphia, and Department of Pediatrics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA.
Matthew TestDivision of Hospital Medicine, Cincinnati Children's Hospital Medical Center, Cincinnati, OH.
Samir S ShahDepartment of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH; Division of Hospital Medicine, Cincinnati Children's Hospital Medical Center, Cincinnati, OH; Division of Infectious Diseases, Cincinnati Children's Hospital Medical Center, Cincinnati, OH.
Cincinnati Children's Hospital Medical Center · USChildren's Hospital of Philadelphia · US

Funding

Cincinnati Center for Clinical and Translational Sciences and TrainingUL1TR000077 · NCATS · UNIVERSITY OF CINCINNATI · PI HEUBI, JAMES E., TSEVAT, JOEL · 2012 to 2014
$9.9M
Cincinnati Center for Clinical and Translational Sciences and TrainingKL2TR000078 · NCATS · UNIVERSITY OF CINCINNATI · PI HEUBI, JAMES E., TSEVAT, JOEL · 2012 to 2014
$1.5M
NCATS NIH HHS KL2 TR000078NCATS NIH HHS UL1 TR000077
6 · The paper itself

Abstract

objectiveTo describe variation across US pediatric hospitals in the utilization of resources not recommended for routine use by the American Academy of Pediatrics guideline for infants hospitalized with bronchiolitis and to examine the association between resource utilization and disposition outcomes. STUDY

designWe conducted a cross-sectional study of infants ≤12 months hospitalized for bronchiolitis from 2007-2012 at 42 hospitals contributing data to the Pediatric Health Information System. Patients with asthma were excluded. The primary outcome was hospital-level variation in utilization of 5 resources not recommended for routine use: albuterol, racemic epinephrine, corticosteroids, chest radiography, and antibiotics. We also examined the association of resource utilization with length of stay (LOS) and readmission.

resultsIn total, 64,994 hospitalizations were analyzed. After adjustment for patient characteristics, albuterol (median, 52.4%; range, 3.5%-81%), racemic epinephrine (20.1%; 0.6%-78.8%), and chest radiography (54.9%; 24.1%-76.7%) had the greatest variation across hospitals. Utilization of albuterol, racemic epinephrine, and antibiotics did not change significantly over time compared with small decreases in corticosteroid (3.3%) and chest radiography (8.6%) use over the study period. Utilization of each resource was significantly associated with increased LOS without concomitant decreased odds of readmission.

conclusionsSubstantial use and variation in 5 resources not recommended for routine use by the American Academy of Pediatrics bronchiolitis guideline persists with increased utilization associated with increased LOS without the benefit of decreased readmission. Future work should focus on developing processes that can be widely disseminated and easily implemented to minimize unwarranted practice variation when evidence and guidelines exist.

Indexed as

Guideline AdherenceAdrenal Cortex HormonesAlbuterolBronchiolitisBronchodilator AgentsCohort StudiesCross-Sectional StudiesEpinephrineEvidence-Based MedicineFemaleHospitalizationHospitals, PediatricHumansInfantInfant, NewbornLength of StayAdrenal Cortex HormonesAlbuterolBronchodilator AgentsEpinephrine

Identifiers

PMID25015578
PMCPMC4177351
OpenAlexW2016420907

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.