ReviewNeurosurgical review2014
Nerve repair: toward a sutureless approach.
Review in Neurosurgical review, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed.
- Experimental Study on the Process and Performance of Laser Repair of Esophageal Tissue Adding ICG and CNT.Journal of biophotonics · 2026Article
- Sutured versus Sutureless Dural Substitutes: Experience from a Government Tertiary Care Hospital in India.Asian journal of neurosurgery · 2026Article
- Biomechanical Evaluation of a Novel Sutureless Hydrogel Device for Peripheral Nerve Repair.Bioengineering (Basel, Switzerland) · 2026Article
- Early Surgical Repair for Temporal Branch of Facial Nerve Injuries: A Retrospective Analysis of Functional Outcomes.Aesthetic plastic surgery · 2025Article
- A Novel Atraumatic Polymer-Assisted Peripheral Nerve Repair Device Compared With Microsurgical Neurorrhaphy.Journal of hand surgery global online · 2025Article
- Reconstruction of resected unilateral phrenic nerve using autologous intercostal nerve during malignant mediastinal tumor resection.General thoracic and cardiovascular surgery · 2025Article
- Targeted muscle reinnervation in upper extremity amputations.European journal of orthopaedic surgery & traumatology : orthopedie traumatologie · 2024Review
- Biomechanical Evaluation of an Atraumatic Polymer-assisted Peripheral Nerve Repair System Compared with Conventional Neurorrhaphy Techniques.Plastic and reconstructive surgery. Global open · 2024Article
- Nerve Regeneration after a Nerve Graft in a Rat Model: The Effectiveness of Fibrin Glue.Journal of personalized medicine · 2024Article
- Progress of tissue adhesives based on proteins and synthetic polymers.Biomaterials research · 2023Review
- Advances of Direct Peripheral Nerve Repair Techniques: Do We Already Have Enough Scientific Evidence?Indian journal of orthopaedics · 2023Review
- Epineural Neurorrhaphy of a Large Nerve Defect Due to IatroGenic Sciatic Nerve Injury in a Maltese Dog.Veterinary sciences · 2022Article
- A Comprehensive Approach to Facial Reanimation: A Systematic Review.Journal of clinical medicine · 2022Review
- Characterization and Ex Vivo Application of Indocyanine Green Chitosan Patches in Dura Mater Laser Bonding.Polymers · 2021Article
- COMSOL Multiphysics® modelling of oxygen diffusion through a cellulose nanofibril conduit employed for peripheral nerve repair.Biomedical engineering online · 2021Article
- Finite Element Analysis of Glucose Diffusivity in Cellulose Nanofibril Peripheral Nerve Conduits.Cellulose (London, England) · 2021Article
- Adhesive Tissue Engineered Scaffolds: Mechanisms and Applications.Frontiers in bioengineering and biotechnology · 2021Review
- Laryngeal adductor function following potassium titanyl phosphate laser welding of the recurrent laryngeal nerve.The Laryngoscope · 2020Article
- Article
- Photocrosslinkable Gelatin/Tropoelastin Hydrogel Adhesives for Peripheral Nerve Repair.Tissue engineering. Part A · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Peripheral nerve repair for complete section injuries employ reconstructive techniques that invariably require sutures in their application. Sutures are unable to seal the nerve, thus incapable of preventing leakage of important intraneural fluids from the regenerating nerve. Furthermore, sutures are technically demanding to apply for direct repairs and often induce detrimental scarring that impedes healing and functional recovery. To overcome these limitations, biocompatible and biodegradable glues have been used to seal and repair peripheral nerves. Although creating a sufficient seal, they can lack flexibility and present infection risks or cytotoxicity. Other adhesive biomaterials have recently emerged into practice that are usually based on proteins such as albumin and collagen or polysaccharides like chitosan. These adhesives form their union to nerve tissue by either photothermal (tissue welding) or photochemical (tissue bonding) activation with laser light. These biomaterial adhesives offer significant advantages over sutures, such as their capacity to unite and seal the epineurium, ease of application, reduced invasiveness and add the potential for drug delivery in situ to facilitate regeneration. This paper reviews a number of different peripheral nerve repair (or reconstructive) techniques currently used clinically and in experimental procedures for nerve injuries with or without tissue deficit.
Indexed as
Identifiers
25015388What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.