ArticleGenome research2014
Genomic analysis of the causative agents of coccidiosis in domestic chickens.
Article in Genome research, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 125 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
125 citing papers in PubMed, 253 citations in OpenAlex.
- Review on anticoccidial vaccine development for chickens: Past progress, modern methods, and production bottlenecks.Poultry science · 2026Review
- Transcriptomic Analysis of Domestic Ducks' Proventriculus Infected withVeterinary sciences · 2026Article
- SenescentMicroorganisms · 2026Article
- Molecular characterization of Eimeria necatrix surface antigen SAG8 and SAG36 genes and their immunoprotective efficacy in chicken.BMC veterinary research · 2026Article
- Target gene mutation discovery and amplicon sequencing for evaluating maduramicin resistance in Eimeria tenella.Communications biology · 2025Article
- An Integrated Model of Biphasic Apoptosis in Avian Coccidiosis: Molecular Networks and Host-Parasite Interplay.Animals : an open access journal from MDPI · 2025Review
- Eimeria tenella apical membrane 2 overexpression enhances pathogenicity and immunity in chickens.Parasites & vectors · 2025Article
- Comparative genomic analysis of fiveMicrobial genomics · 2025Article
- Comparative analysis of model antigen expression level driven by the microneme protein promoters in Eimeria tenella.Poultry science · 2025Article
- Metagenomic Insight into Cecal Microbiota Shifts in Broiler Chicks FollowingMicroorganisms · 2025Article
- Chromosomal scale assembly and functional annotation of the apicomplexan parasite Eimeria acervulina.Scientific data · 2025Article
- Molecular mechanisms of surface antigen suppression by ApiAP2 and its implications for vaccine development.Veterinary research · 2025Article
- Genetic manipulation for the non-model protozoaniScience · 2025Review
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- Molecular and histopathological characterization ofFrontiers in veterinary science · 2025Article
- Temporal changes in cecal luminal and mucosal microbiota of broiler chickens with clinical coccidiosis (Eimeria maxima).PloS one · 2025Article
- Development of a molecular assay for the determination of Eimeria tenella oocyst viability.Parasitology research · 2024Article
- Anticoccidial activity of the secondary metabolites in alpine plants frequently ingested by wild Japanese rock ptarmigans.International journal for parasitology. Parasites and wildlife · 2024Article
- Insights into genomic sequence diversity of the SAG surface antigen superfamily in geographically diverse Eimeria tenella isolates.Scientific reports · 2024Article
65 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
35 authors at 15 institutions in 10 countries.
Funding
Abstract
Global production of chickens has trebled in the past two decades and they are now the most important source of dietary animal protein worldwide. Chickens are subject to many infectious diseases that reduce their performance and productivity. Coccidiosis, caused by apicomplexan protozoa of the genus Eimeria, is one of the most important poultry diseases. Understanding the biology of Eimeria parasites underpins development of new drugs and vaccines needed to improve global food security. We have produced annotated genome sequences of all seven species of Eimeria that infect domestic chickens, which reveal the full extent of previously described repeat-rich and repeat-poor regions and show that these parasites possess the most repeat-rich proteomes ever described. Furthermore, while no other apicomplexan has been found to possess retrotransposons, Eimeria is home to a family of chromoviruses. Analysis of Eimeria genes involved in basic biology and host-parasite interaction highlights adaptations to a relatively simple developmental life cycle and a complex array of co-expressed surface proteins involved in host cell binding.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.