ArticleMethods in molecular biology (Clifton, N.J.)2014
Generation and identification of tumor-evoked regulatory B cells.
Article in Methods in molecular biology (Clifton, N.J.), 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
8 citing papers in PubMed.
- The prometastatic relevance of tumor-infiltrating B lymphocytes in laryngeal squamous cell carcinoma.Clinical & translational immunology · 2023Article
- Article
- Machine learning and BP neural network revealed abnormal B cell infiltration predicts the survival of lung cancer patients.Frontiers in oncology · 2022Article
- TGF-βR inhibitor SB431542 restores immune suppression induced by regulatory B-T cell axis and decreases tumour burden in murine fibrosarcoma.Cancer immunology, immunotherapy : CII · 2021Article
- Expanding Diversity and Common Goal of Regulatory T and B Cells. II: In Allergy, Malignancy, and Transplantation.Archivum immunologiae et therapiae experimentalis · 2017Review
- Positive and negative functions of B lymphocytes in tumors.Oncotarget · 2016Review
- Crosstalk of carcinoembryonic antigen and transforming growth factor-β via their receptors: comparing human and canine cancer.Cancer immunology, immunotherapy : CII · 2015Review
- Activation of glioma cells generates immune tolerant NKT cells.The Journal of biological chemistry · 2014Article
Corrections and comments
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Authors and funding
3 authors.
Funding
Abstract
The involvement of Bregs in cancer remains poorly understood despite their well-documented regulation of responses to the self and protection from harmful autoimmunity. We recently discovered a unique regulatory B cell subset evoked by breast cancer to mediate protection of metastasizing cancer cells. These results together with the wealth of findings of the last 40 years on B cells in tumorigenesis suggest the existence of additional cancer Bregs modulating anticancer responses. To facilitate the search for them, here we provide our detailed protocol for the characterization and generation of tumor-evoked regulatory B cells. Wherever applicable, we also discuss nuances and uniqueness of a Breg study in cancer to warn potential pitfalls.
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Registered trials
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