ReviewJournal of clinical gastroenterology2014
Current and emerging treatment options for fecal incontinence.
Review in Journal of clinical gastroenterology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
24 citing papers in PubMed, 3 syntheses or guidelines pooled it, 52 citations in OpenAlex.
- Management of patients with rectal prolapse: the 2017 Dutch guidelines.Techniques in coloproctology · 2018Guideline
- Can incontinence be cured? A systematic review of cure rates.BMC medicine · 2017Pooled it
- ANMS-ESNM position paper and consensus guidelines on biofeedback therapy for anorectal disorders.Neurogastroenterology and motility · 2015Guideline
- Randomized controlled trial of an Internet-of-Medical-Things device for patient-guided anorectal biofeedback therapy.PloS one · 2024Trial
- Libertas: a phase II placebo-controlled study of NRL001 in patients with faecal incontinence showed an unexpected and sustained placebo response.International journal of colorectal disease · 2016Trial
- The Japan Society of Coloproctology Practice Guidelines for Fecal Incontinence 2024 (Revised Second Edition).Journal of the anus, rectum and colon · 2026Review
- The association between fecal incontinence and asthma among adult Americans: evidence from NHANES 2005-2010.Frontiers in medicine · 2025Article
- Clinical Outcomes and Safety Profile of a Dextranomer-Hyaluronic Acid Hybrid Filler: A Case Series Analysis.Journal of cosmetic dermatology · 2025Article
- Pelvic Floor Rehabilitation After Rectal Cancer Surgery One-year follow-up of a Multicenter Randomized Clinical Trial (FORCE trial).Annals of surgery · 2024Article
- The Impact of Nutritional Therapy on Gastrointestinal Motility in Older Adults.Healthcare (Basel, Switzerland) · 2023Review
- Differences in fatigability of muscles involved in fecal continence: Potential clinical ramifications.Physiological reports · 2021Article
- Comparative effectiveness of biofeedback and injectable bulking agents for treatment of fecal incontinence: Design and methods.Contemporary clinical trials · 2021Article
- The development of a faecal incontinence core outcome set: an international Delphi study protocol.International journal of colorectal disease · 2021Article
- Japanese Practice Guidelines for Fecal Incontinence Part 2-Examination and Conservative Treatment for Fecal Incontinence- English Version.Journal of the anus, rectum and colon · 2021Review
- Clinical Evaluation of a Patient With Symptoms of Colonic or Anorectal Motility Disorders.Journal of neurogastroenterology and motility · 2020Review
- Low Anterior Resection Syndrome.Current gastroenterology reports · 2020Review
- Article
- Effects of Dietary Guidance without Dietary Fiber Supplements on the Symptoms, Quality of Life, and Dietary Intake in Patients with Fecal Incontinence.Journal of the anus, rectum and colon · 2020Article
- Etiology and management of low anterior resection syndrome based on the normal defecation mechanism.Surgery today · 2019Review
- Surgical Interventions and the Use of Device-Aided Therapy for the Treatment of Fecal Incontinence and Defecatory Disorders.Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association · 2017Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Fecal incontinence (FI) is a multifactorial disorder that imposes considerable social and economic burdens. The aim of this article is to provide an overview of current and emerging treatment options for FI. A MEDLINE search was conducted for English-language articles related to FI prevalence, etiology, diagnosis, and treatment published from January 1, 1990 through June 1, 2013. The search was extended to unpublished trials on ClinicalTrials.gov and relevant publications cited in included articles. Conservative approaches, including dietary modifications, medications, muscle-strengthening exercises, and biofeedback, have been shown to provide short-term benefits. Transcutaneous electrical stimulation was considered ineffective in a randomized clinical trial. Unlike initial studies, sacral nerve stimulation has shown reasonable short-term effectiveness and some complications. Dynamic graciloplasty and artificial sphincter and bowel devices lack randomized controlled trials and have shown inconsistent results and high rates of explantation. Of injectable bulking agents, dextranomer microspheres in non-animal stabilized hyaluronic acid (NASHA Dx) has shown significant improvement in incontinence scores and frequency of incontinence episodes, with generally mild adverse effects. For the treatment of FI, conservative measures and biofeedback therapy are modestly effective. When conservative therapies are ineffective, invasive procedures, including sacral nerve stimulation, may be considered, but they are associated with complications and lack randomized, controlled trials. Bulking agents may be an appropriate alternative therapy to consider before more aggressive therapies in patients who fail conservative therapies.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.