Evidence map›Paper›PMID 25014072›Full record

SynthesisPloS one2014

Hemoglobin A1c for diagnosis of postpartum abnormal glucose tolerance among women with gestational diabetes mellitus: diagnostic meta-analysis.

Xudong Su, Zhaoyan Zhang, Xinye Qu, Yaqiang Tian, Guangzhen Zhang

Registry-linked trialOpen access · goldAbstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in PloS one, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03946631 (Immediate Postpartum Screening for Diabetes Mellitus in Women With Gestational Diabetes.), which is not on this map. Cited by 19 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 2 pooled it
5.0field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03946631 terminatednot on this mapstarted 2019, after this paper: background citation

Immediate Postpartum Screening for Diabetes Mellitus in Women With Gestational Diabetes.

TypeobservationalSponsorPediatrixRan2019 to 2022Enrolled21ConditionsDiabetes, Gestational Diabetes, Diabetes Mellitus, Type 2Arms2 hour glucose tolerance test using 75g glucose drink
3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 2 syntheses or guidelines pooled it, 41 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Review
  4. Article
  5. Article
  6. Carbohydrate Intake and Oral Glucose Tolerance Test Results in the Postpartum Period.The Journal of clinical endocrinology and metabolism · 2023
    Article
  7. Pregnancy as an opportunity to prevent type 2 diabetes mellitus: FIGO Best Practice Advice.International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics · 2023
    Review
  8. Article
  9. Article
  10. Article
  11. Review
  12. Optimizing postpartum care for the patient with gestational diabetes mellitus.American journal of obstetrics and gynecology · 2017
    Article
  13. Article
  14. Review
  15. Article
  16. Is There a Role for HbA1c in Pregnancy?Current diabetes reports · 2016
    Review
  17. Review
  18. Article
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Xudong SuDepartment of Endocrinology, Liaocheng People's Hospital, Liaocheng, China.
Zhaoyan ZhangDepartment of Gynaecology and Obstetrics, Women and Children Hospital, Liaocheng, China.
Xinye QuDepartment of Gynaecology and Obstetrics, Women and Children Hospital, Liaocheng, China.
Yaqiang TianDepartment of Endocrinology, Liaocheng People's Hospital, Liaocheng, China.
Guangzhen ZhangDepartment of Endocrinology, Liaocheng People's Hospital, Liaocheng, China.
Liaocheng People's Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo evaluate the accuracy of glycosylated hemoglobin A1c (HbA1c) for the diagnosis of postpartum abnormal glucose tolerance among women with gestational diabetes mellitus (GDM).

methodsAfter a systematic review of related studies, the sensitivity, specificity, positive likelihood ratio (PLR), negative likelihood ratio (NLR), diagnostic odds ratio (DOR), and other measures about the accuracy of HbA1c in the diagnosis of postpartum abnormal glucose tolerance were pooled using random-effects models. The summary receiver operating characteristic (SROC) curve was used to summarize the overall test performance.

resultsSix studies met our inclusion criteria. The pooled results on SEN, SPE, PLR, NLR, and DOR were 0.36 (95% CI 0.23-0.52), 0.85 (95% CI 0.73-0.92), 2.4 (95% CI 1.6-3.6), 0.75 (95% CI 0.63-0.88) and 3 (95% CI 2-5). The area under the summary receiver operating characteristic (SROC) curve was 0.67 with a Q value of 0.63.

conclusionsMeasurement of HbA1c alone is not a sensitive test to detect abnormal glucose tolerance in women with prior GDM.

Indexed as

Models, StatisticalAdultArea Under CurveBlood GlucoseDiabetes, GestationalFemaleGlucose IntoleranceGlycated HemoglobinHumansPostpartum PeriodPregnancyROC CurveBlood GlucoseGlycated Hemoglobinhemoglobin A1c protein, human

Identifiers

PMID25014072
PMCPMC4094518
OpenAlexW2073358576

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.