Evidence map›Paper›PMID 25013753›Full record

ArticleGenomics data2014

Genome-wide analysis of HOXC9-induced neuronal differentiation of neuroblastoma cells.

Xiangwei Wang, Liqun Yang, Jeong-Hyeon Choi, Eiko Kitamura, Chang-Sheng Chang, Jane Ding, Eun J Lee, Hongjuan Cui, Han-Fei Ding

Open access · goldAbstract read
In one paragraph

Article in Genomics data, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.9field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 11 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 2 countries.

Xiangwei Wang
Liqun Yang
Jeong-Hyeon Choi
Eiko Kitamura
Chang-Sheng Chang
Jane Ding
Eun J Lee
Hongjuan Cui
Han-Fei Ding
Augusta University · USGeorgia Regents Medical Center · USIgenbio (United States) · USState Key Laboratory of Silkworm Genomic BiologyArmy Medical University · CN

Funding

The oncogenic basis of Bmi-1 in neuroblastoma developmentR01CA124982 · NCI · UNIVERSITY OF TOLEDO HEALTH SCI CAMPUS · PI DING, HAN-FEI · 2007 to 2010
$1.1M
NCI NIH HHS R01 CA124982
6 · The paper itself

Abstract

Induction of differentiation is a therapeutic strategy in neuroblastoma, a common pediatric cancer of the sympathetic nervous system. The homeobox protein HOXC9 is a key regulator of neuroblastoma differentiation. To gain a molecular understanding of the function of HOXC9 in promoting differentiation of neuroblastoma cells, we conducted a genome-wide analysis of the HOXC9-induced differentiation program by microarray gene expression profiling and chromatin immunoprecipitation in combination with massively parallel sequencing (ChIP-seq). Here we describe in details the experimental system, methods, and quality control for the generation of the microarray and ChIP-seq data associated with our recent publication [1].

Identifiers

PMID25013753
PMCPMC4084856
OpenAlexW1965226394

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.