Evidence map›Paper›PMID 25013619›Full record

ArticleInternational journal of organ transplantation medicine2012

Invasive fungal infections after renal transplantation.

S Ezzatzadegan, S Chen, J R Chapman

Abstract read
In one paragraph

Article in International journal of organ transplantation medicine, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Risk factors for development and mortality of invasive pulmonary Aspergillosis in kidney transplantation recipients.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2020
    Article
  5. Article
  6. Article
  7. Invasive fungal infections following kidney transplantation.International journal of organ transplantation medicine · 2012
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

S EzzatzadeganShiraz Nephrology Urology Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.
S ChenCenter for Infectious Diseases and Microbiology, Westmead Hospital , Westmead, Sydney , NSW, Australia.
J R ChapmanCenter for Transplant and Renal Research, University of Sydney, Westmead Hospital, Sydney , NSW, Australia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundInvasive fungal infection (IFI) is a leading cause of infection-related mortality among kidney allograft recipients.

objectiveTo estimate the incidence and etiology of systemic fungal infection in renal allograft recipients in Sydney transplant facility.

methods471 kidney recipients, transplanted between 2000 and 2010 at the Westmead Hospital renal transplantation center, Sydney, Australia, were retrospectively surveyed.

resultsIFI developed in 10 (2.1%) of 471 patients. With a mean±SD new kidney transplants per year of 42.9±13, the mean±SD incidence of IFI was 0.9±0.6 for each year of transplantation. 4 patients had received kidneys from living donors and 7 from cadavers with a mean±SD age of 50.5±14 years. The mean time to IFI was 33 months after transplantation with majority within the first 2 years. Cryptococcus neoformans was responsible for 50% of episodes (n=5) followed by Aspergillus fumigatus (n=3), and Pseudallescheria boydii (n=3); there was a single case of mucurmycosis. Lungs (n=5) followed by meninges (n=4) and skin (n=3) were the most commonly involved sites.

conclusionIFI remains a major concern in renal transplantation. A high index of suspicion is required for early diagnosis and treatment to reduce the mortality. In this regard, appropriate diagnostic tests are necessary, particularly for C. neoformans.

Indexed as

CryptococcosisFungal infectionsRenal transplantation

Identifiers

PMID25013619
PMCPMC4089273

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