ArticleCase reports in medicine2014
Histoplasmosis presenting as granulomatous hepatitis: case report and review of the literature.
Article in Case reports in medicine, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
15 citing papers in PubMed, 36 citations in OpenAlex.
- Disseminated liver histoplasmosis in an immunocompetent individual cured by liver transplantation and voriconazole from China: A case report.World journal of gastroenterology · 2025Article
- Gastrointestinal Histoplasmosis: A Descriptive Review, 2001-2021.Life (Basel, Switzerland) · 2023Review
- Development of an Interferon-Gamma Release Assay (IGRA) to Aid Diagnosis of Histoplasmosis.Journal of clinical microbiology · 2022Article
- Increasing Alkaline Phosphatase as the Primary Manifestation of Disseminated Histoplasmosis in an AIDS Patient Without Pulmonary Disease.ACG case reports journal · 2022Article
- Hepatic Histoplasmosis: An Update.Journal of clinical and translational hepatology · 2022Review
- Article
- Disseminated histoplasmosis leading to end stage liver failure in immunocompetent patient: case report and review of literature.Radiology case reports · 2021Article
- Acute Liver Failure and Fever of Unknown Origin.Open forum infectious diseases · 2021Article
- Disseminated Histoplasmosis in a Patient With Multiple Sclerosis Treated With Fingolimod.Neurology(R) neuroimmunology & neuroinflammation · 2021Article
- Cholestasis and disseminated histoplasmosis in a psoriatic patient on infliximab: case report and review of literature.BMC gastroenterology · 2020Review
- Organ-specific mechanisms linking innate and adaptive antifungal immunity.Seminars in cell & developmental biology · 2019Review
- Asymptomatic Histoplasma Pylephlebitis in an Orthotopic Liver Transplant Recipient: A Case Report and Literature Review.Mycopathologia · 2019Review
- Histoplasmosis hepatitis after orthotopic liver transplantation.Journal of surgical case reports · 2017Article
- Erythema induratum of Bazin and Ponçet's arthropathy as epiphenomena of hepatic tuberculosis.BMJ case reports · 2016Article
- [Hepatic and Peritoneal Histoplasmosis Simulating Another Pathology].Acta gastroenterologica LatinoamericanaArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background. Histoplasma capsulatum is the most common endemic mycosis in the United States and is a frequent cause of opportunistic infection in immunodeficient hosts. Histoplasmosis is most often self-limiting and goes unrecognized in the immunocompetent population but can progress to disseminated histoplasmosis in patients with an impaired immune system. Liver involvement as a part of disseminated histoplasmosis which usually originates in the lung is well known. However, extrapulmonary hepatic histoplasmosis as a primary manifestation is extremely rare. Case Presentation. We report a rare case of histoplasmosis that presented as persistent fever and abnormal liver function tests in a 66-year-old female with rheumatoid arthritis, receiving infliximab. Conclusion. Emphasizing histoplasmosis as a major cause of acute granulomatous hepatitis and fever of unknown origin in cell mediated immunodeficient population, this case highlights the need for high index of suspicion and the importance of prompt diagnosis since any delay of treatment can be life threatening in this population.
Identifiers
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.