Evidence map›Paper›PMID 25013389›Full record

ArticleGastroenterology & hepatology2014

Gastric intestinal metaplasia and early gastric cancer in the west: a changing paradigm.

Justin M Gomez, Andrew Y Wang

Registry-linked trialAbstract read
In one paragraph

Article in Gastroenterology & hepatology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04720521 (Application of OpticalEnhancement Endoscopy(OE) in Diagnosis of Early Gastric Cancer), which is not on this map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04720521 naunknown statusnot on this mapstarted 2019, after this paper: background citation

Application of OpticalEnhancement Endoscopy(OE) in Diagnosis of Early Gastric Cancer: a Multicenter, Prospective, Randomized Controlled Study

TypeinterventionalSponsorChanghai HospitalRan2019 to 2021Enrolled2,454ConditionsHigh Risk Population of Gastric CancerArmsOE+white light
3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

  1. Trial
  2. Article
  3. Identifying the pre-malignant stomach: from guidelines to practice.Translational gastroenterology and hepatology · 2022
    Review
  4. International cost-effectiveness analysis evaluating endoscopic screening for gastric cancer for populations with low and high risk.Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association · 2021
    Article
  5. Article
  6. Demographic Profile of Gastric Cancer in Afghanistan.Indian journal of surgical oncology · 2020
    Article
  7. The Small Bowel Cancer Incidence Enigma.Pathology oncology research : POR · 2020
    Review
  8. Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Anatomical predilection of intestinal metaplasia based on 78,335 endoscopic cases.Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Justin M GomezDr Gomez is a clinical instructor in the Department of Medicine and Dr Wang is an associate professor of medicine in the Division of Gastroenterology and Hepatology at the University of Virginia in Charlottesville, Virginia.
Andrew Y WangDr Gomez is a clinical instructor in the Department of Medicine and Dr Wang is an associate professor of medicine in the Division of Gastroenterology and Hepatology at the University of Virginia in Charlottesville, Virginia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Gastric cancer remains the fifth leading cancer diagnosis worldwide, and it is the third leading cause of cancer-related mortality. The incidence of gastric cancer within the United States, however, has remained substantially lower than elsewhere, which has led to a lack of screening and surveillance in clinical practice. Patients with known premalignant lesions, such as gastric intestinal metaplasia, which can increase the risk of gastric cancer by as much as 6-fold, might benefit from surveillance guidelines to detect gastric cancer at an earlier, potentially curative stage. Chro-moendoscopy with optical magnification, narrow-band imaging, and other image-enhanced endoscopic techniques are commercially available to assist in the diagnosis of premalignant gastric lesions and early gastric cancer. Furthermore, endoscopic mucosal resection and endoscopic submucosal dissection have become more widely available and offer potentially curative endoscopic resection for dysplastic lesions of the stomach and early gastric cancers, which is an alternative to traditional surgical resection.

Indexed as

Early gastric cancerendoscopic submucosal dissectionesophagogastroduodenoscopygastric intestinal metaplasiastaging

Identifiers

PMID25013389
PMCPMC4080873

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.