Evidence map›Paper›PMID 25012675›Full record

ArticleAJNR. American journal of neuroradiology

Safety and effectiveness of sacroplasty: a large single-center experience.

A C Gupta, R V Chandra, A J Yoo, T M Leslie-Mazwi, D L Bell, B P Mehta, T L Vanderboom, J D Rabinov, M Larvie, J A Hirsch

Open access · bronzeAbstract read
In one paragraph

Article in AJNR. American journal of neuroradiology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
5.3field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 56 citations in OpenAlex.

  1. Trial
  2. Finite element validation and short-term clinical outcomes of robot-assisted percutaneous microwave ablation plus cement augmentation and sacroiliac screw fixation for upper sacral (S1-S2) metastases.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026
    Article
  3. Sacral insufficiency fracture: a single-center experience of 185 patients with a minimum 5-year follow-up.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

A C GuptaFrom the Department of Radiology (A.C.G., A.J.Y., T.M.L.-M., D.L.B., B.P.M., T.L.V., J.D.R., M.L., J.A.H.), Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts.
R V ChandraDepartment of Radiology (R.V.C.), Monash Health, and Department of Surgery, Monash University, Melbourne, Australia.
A J YooFrom the Department of Radiology (A.C.G., A.J.Y., T.M.L.-M., D.L.B., B.P.M., T.L.V., J.D.R., M.L., J.A.H.), Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts.
T M Leslie-MazwiFrom the Department of Radiology (A.C.G., A.J.Y., T.M.L.-M., D.L.B., B.P.M., T.L.V., J.D.R., M.L., J.A.H.), Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts.
D L BellFrom the Department of Radiology (A.C.G., A.J.Y., T.M.L.-M., D.L.B., B.P.M., T.L.V., J.D.R., M.L., J.A.H.), Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts.
B P MehtaFrom the Department of Radiology (A.C.G., A.J.Y., T.M.L.-M., D.L.B., B.P.M., T.L.V., J.D.R., M.L., J.A.H.), Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts.
T L VanderboomFrom the Department of Radiology (A.C.G., A.J.Y., T.M.L.-M., D.L.B., B.P.M., T.L.V., J.D.R., M.L., J.A.H.), Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts.
J D RabinovFrom the Department of Radiology (A.C.G., A.J.Y., T.M.L.-M., D.L.B., B.P.M., T.L.V., J.D.R., M.L., J.A.H.), Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts.
M LarvieFrom the Department of Radiology (A.C.G., A.J.Y., T.M.L.-M., D.L.B., B.P.M., T.L.V., J.D.R., M.L., J.A.H.), Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts.
J A HirschFrom the Department of Radiology (A.C.G., A.J.Y., T.M.L.-M., D.L.B., B.P.M., T.L.V., J.D.R., M.L., J.A.H.), Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts jahirsch@partners.org jahirsch@mgh.harvard.edu.
Harvard University · USMassachusetts General Hospital · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

background and purposeSacral insufficiency fractures are a common cause of severe low back pain and immobilization in patients with osteoporosis or cancer. Current practice guideline recommendations range from analgesia and physical therapy to resection with surgical fixation. We sought to assess the safety and effectiveness of sacroplasty, an emerging minimally invasive treatment. MATERIALS AND

methodsWe performed a retrospective review of institutional databases for percutaneous sacroplasty performed between January 2004 and September 2013. Demographic and procedural data and pre- and posttreatment Visual Analog Scale, Functional Mobility Scale, and Analgesic Scale scores were reviewed. Overall response was rated by using a 4-point scale (1, complete resolution of pain; 2, improvement of pain; 3, no change; 4, worsened pain) assessed at short-term follow-up.

resultsFifty-three patients were included; most (83%) were female. Fracture etiology was cancer-related (55%), osteoporotic insufficiency (30%), and minor trauma (15%). No major complication or procedure-related morbidity occurred. There were statistically significant decreases in the Visual Analog Scale (P < .001), Functional Mobility Scale (P < .001), and Analgesic Scale scores (P < .01) in 27 patients with recorded data: pretreatment Visual Analog Scale (median [interquartile range], 9.0 [8.0-10.0]); Functional Mobility Scale, 3.0 (2.0-3.0); and Analgesic Scale scores, 3.0 (3.0-4.0) were reduced to 3.0 (0.0-5.8), 1.0 (0.25-2.8), and 3.0 (2.0-3.8) posttreatment. When we used the overall 4-point score at a mean of 27 days, 93% (n = 45) reported complete resolution or improvement in overall pain.

conclusionsIn this single-center cohort, sacroplasty was a safe and effective procedure. There were significant short-term gains in pain relief, increased mobility, and decreased dependence on pain medication.

Indexed as

AdultAgedBone NeoplasmsFemaleHumansMaleMiddle AgedOrthopedic ProceduresOsteoporosisRetrospective StudiesSacrumSpinal FracturesTreatment Outcome

Identifiers

PMID25012675
PMCPMC7965161
OpenAlexW1991724601

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.