ArticleJournal of affective disorders2014
Association of testosterone levels and future suicide attempts in females with bipolar disorder.
Article in Journal of affective disorders, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
20 citing papers in PubMed, 53 citations in OpenAlex.
- Neuroendocrine abnormalities as predictors of suicidal ideation in bipolar disorder patients during depressive episodes: a cross-sectional study.BMC psychiatry · 2025Article
- Biological Basis for the Formation of Suicidal Behavior: A Review.Medical journal of the Islamic Republic of Iran · 2025Review
- Trace Lithium for Suicide Prevention and Dementia Prevention: A Qualitative Review.Pharmaceuticals (Basel, Switzerland) · 2024Review
- Association between testosterone and cancers risk in women: a two-sample Mendelian randomization study.Discover oncology · 2023Article
- Heterogeneity of non-suicidal self-injury behavior in adolescents with depression: latent class analysis.BMC psychiatry · 2023Article
- Testosterone and Suicidal Behavior in Bipolar Disorder.International journal of environmental research and public health · 2023Article
- Psychobiological risk factors for suicidal thoughts and behaviors in adolescence: a consideration of the role of puberty.Molecular psychiatry · 2022Review
- New frontiers in suicide vulnerability: immune system and sex hormones.Brain, behavior, & immunity - health · 2021Article
- The Relationship Between Suicide Attempt and Gonadotropins, Gonadal Hormones, and Cortisol in Females.Alpha psychiatry · 2021Article
- Male-specific association of the 2p25 region with suicide attempt in bipolar disorder.Journal of psychiatric research · 2020Article
- Lipids and Suicide Risk.Current topics in behavioral neurosciences · 2020Article
- Sex differences in schizophrenia, bipolar disorder, and post-traumatic stress disorder: Are gonadal hormones the link?British journal of pharmacology · 2019Review
- Role of HPA and the HPG Axis Interaction in Testosterone-Mediated Learned Helpless Behavior.Molecular neurobiology · 2019Article
- Testosterone is related to GABA+ levels in the posterior-cingulate in unmedicated depressed women during reproductive life.Journal of affective disorders · 2019Article
- Comparison of salivary testosterone levels in different phases of bipolar I disorder and control group.Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences · 2018Article
- Commentary: CSF and Plasma Testosterone in Attempted Suicide.Frontiers in public health · 2017Article
- Commentary: Exogenous Testosterone Rapidly Increases Aggressive Behavior in Dominant and Impulsive Men.Frontiers in public health · 2016Article
- An exploration of testosterone levels in patients with bipolar disorder.BJPsych open · 2015Article
- Are There any Relationships between Latent Toxoplasma gondii Infection, Testosterone Elevation, and Risk of Autism Spectrum Disorder?Frontiers in behavioral neuroscience · 2014Review
- Neighborhood socioeconomic status during childhood versus puberty in relation to endogenous sex hormone levels in adult women.Nursing researchObservational
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 1 country.
Funding
Abstract
backgroundConsiderable evidence suggests that testosterone may play a role in the pathophysiology of mood disorders in females. This is the first prospective study to examine whether blood testosterone levels predict suicide attempts in females with bipolar disorder.
methodsFemales with a DSM-IV diagnosis of a bipolar disorder in a depressive or mixed episode with at least one past suicide attempt were enrolled. Demographic and clinical parameters were assessed and recorded. Plasma testosterone was assayed using a double antibody radioimmunoassay procedure. Patients were followed up prospectively for up to 2.5 years.
resultsAt baseline, testosterone levels positively correlated with the number of previous major depressive episodes and suicide attempts. Cox proportional hazards regression analysis found that higher baseline testosterone levels predicted suicide attempts during the follow-up period. LIMITATIONS: A limitation of the study is that the sample size is modest. Another limitation is that we did not have a bipolar nonattempter or healthy volunteer control group for comparison.
conclusionTestosterone levels may predict suicidal behavior in women with bipolar disorder.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.