Evidence map›Paper›PMID 25012172›Full record

ArticleJournal of the American Society of Nephrology : JASN2015

Antagonism of canonical Wnt/β-catenin signaling: taking RAS blockade to the next level?

Jürgen Floege

Abstract readEditorialComment
In one paragraph

Article in Journal of the American Society of Nephrology : JASN, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Review
  5. The Role of Macrophages in Kidney Fibrosis.Frontiers in physiology · 2021
    Review
  6. Article
  7. Wnt/β-catenin regulates blood pressure and kidney injury in rats.Biochimica et biophysica acta. Molecular basis of disease · 2019
    Article
  8. Sustained Activation of Wnt/β-Catenin Signaling Drives AKI to CKD Progression.Journal of the American Society of Nephrology : JASN · 2016
    Article
  9. Review
  10. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

1 author.

Jürgen FloegeDivision of Nephrology and Immunology, RWTH University of Aachen, Aachen, Germany juergen.floege@rwth-aachen.de.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Gene Expression RegulationAnimalsbeta CateninHumansRenin-Angiotensin SystemWnt Signaling Pathwaybeta CateninACE inhibitorsangiotensinchronic kidney diseasefibrosisrenin angiotensin system

Identifiers

PMID25012172
PMCPMC4279747

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.