Evidence map›Paper›PMID 25011549›Full record

ArticleOccupational and environmental medicine2014

Exposure to volatile organic compounds in healthcare settings.

Ryan F LeBouf, M Abbas Virji, Rena Saito, Paul K Henneberger, Nancy Simcox, Aleksandr B Stefaniak

Abstract read
In one paragraph

Article in Occupational and environmental medicine, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Exhaled Breath Analysis in Diagnosis of Malignant Pleural Mesothelioma: Systematic Review.International journal of environmental research and public health · 2020
    Pooled it
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  17. Surgical smoke control with local exhaust ventilation: Experimental study.Journal of occupational and environmental hygiene · 2018
    Article
  18. In vitro toxicological evaluation of surgical smoke from human tissue.Journal of occupational medicine and toxicology (London, England) · 2018
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Ryan F LeBoufNational Institute for Occupational Safety and Health, Morgantown, West Virginia, USA.
M Abbas VirjiNational Institute for Occupational Safety and Health, Morgantown, West Virginia, USA.
Rena SaitoNational Institute for Occupational Safety and Health, Morgantown, West Virginia, USA.
Paul K HennebergerNational Institute for Occupational Safety and Health, Morgantown, West Virginia, USA.
Nancy SimcoxCenter for Indoor Environments and Health, University of Connecticut Health Center, Farmington, Connecticut, USA.
Aleksandr B StefaniakNational Institute for Occupational Safety and Health, Morgantown, West Virginia, USA.

Funding

Intramural CDC HHS CC999999
6 · The paper itself

Abstract

objectivesTo identify and summarise volatile organic compound (VOC) exposure profiles of healthcare occupations.

methodsPersonal (n=143) and mobile area (n=207) evacuated canisters were collected and analysed by a gas chromatograph/mass spectrometer to assess exposures to 14 VOCs among 14 healthcare occupations in five hospitals. Participants were volunteers identified by their supervisors. Summary statistics were calculated by occupation. Principal component analysis (PCA) was used to reduce the 14 analyte inputs to five orthogonal factors and identify occupations that were associated with these factors. Linear regressions were used to assess the association between personal and mobile area samples.

resultsExposure profiles differed among occupations; ethanol had the highest geometric mean (GM) among nursing assistants (∼4900 and ∼1900 µg/m(3), personal and area), and 2-propanol had the highest GM among medical equipment preparers (∼4600 and ∼2000 µg/m(3), personal and area). The highest total personal VOC exposures were among nursing assistants (∼9200 µg/m(3)), licensed practical nurses (∼8700 µg/m(3)) and medical equipment preparers (∼7900 µg/m(3)). The influence of the PCA factors developed from personal exposure estimates varied by occupation, which enabled a comparative assessment of occupations. For example, factor 1, indicative of solvent use, was positively correlated with clinical laboratory and floor stripping/waxing occupations and tasks. Overall, a significant correlation was observed (r=0.88) between matched personal and mobile area samples, but varied considerably by analyte (r=0.23-0.64).

conclusionsHealthcare workers are exposed to a variety of chemicals that vary with the activities and products used during activities. These VOC profiles are useful for estimating exposures for occupational hazard ranking for industrial hygienists as well as epidemiological studies.

Indexed as

Hospitals, VeteransAir Pollutants, OccupationalEnvironmental MonitoringHealth PersonnelHumansOccupational ExposurePrincipal Component AnalysisRegression AnalysisUnited StatesVolatile Organic CompoundsAir Pollutants, OccupationalVolatile Organic Compounds

Identifiers

PMID25011549
PMCPMC4591534

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.