Evidence map›Paper›PMID 25011008›Full record

ReviewFungal genetics and biology : FG & B2014

Fungal model systems and the elucidation of pathogenicity determinants.

Elena Perez-Nadales, Maria Filomena Almeida Nogueira, Clara Baldin, Sónia Castanheira, Mennat El Ghalid, Elisabeth Grund, Klaus Lengeler, Elisabetta Marchegiani, Pankaj Vinod Mehrotra, Marino Moretti and 15 more

Open access · hybridAbstract readReview
In one paragraph

Review in Fungal genetics and biology : FG & B, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 77 papers.

0numbers the graph read from it
0cells of the map it votes in
77citing papers in PubMed
22.4field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

77 citing papers in PubMed, 171 citations in OpenAlex.

  1. Article
  2. Article
  3. Solanaceous vegetables andHorticulture research · 2026
    Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Nanopore Data-Driven T2T Genome Assemblies ofJournal of fungi (Basel, Switzerland) · 2024
    Article
  12. Oral administration of Lactobacillus delbrueckii UFV-H2b20 protects mice against Aspergillus fumigatus lung infection.Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2024
    Article
  13. Comparative Genomic Analyses ofJournal of fungi (Basel, Switzerland) · 2024
    Article
  14. Article
  15. Pyricularia oryzae: Lab star and field scourge.Molecular plant pathology · 2024
    Review
  16. Article
  17. Review
  18. Article
  19. Article
  20. Article

17 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

25 authors at 10 institutions in 5 countries.

Elena Perez-NadalesDepartment of Genetics, Edificio Gregor Mendel, Planta 1. Campus de Rabanales, University of Cordoba, 14071 Cordoba, Spain. Electronic address: ge2penae@uco.es.
Maria Filomena Almeida NogueiraAberdeen Fungal Group, School of Medical Sciences, Institute of Medical Sciences, University of Aberdeen, Aberdeen, UK.
Clara BaldinDepartment of Molecular and Applied Microbiology, Leibniz Institute for Natural Product Research and Infection Biology - Hans Knöll Institute (HKI), Beutembergstr. 11a, 07745 Jena, Germany; Department of Microbiology and Molecular Biology, Institute of Microbiology, Friedrich Schiller University Jena, Beutenbergstr. 11a, 07745 Jena, Germany.
Sónia CastanheiraInstituto de Biología Funcional y GenómicaCSIC, Universidad de Salamanca, 37007 Salamanca, Spain.
Mennat El GhalidDepartment of Genetics, Edificio Gregor Mendel, Planta 1. Campus de Rabanales, University of Cordoba, 14071 Cordoba, Spain.
Elisabeth GrundFunctional Genomics of Plant Pathogenic Fungi, UMR 5240 CNRS-UCB-INSA-Bayer SAS, Bayer CropScience, 69263 Lyon, France.
Klaus LengelerCarlsberg Laboratory, Department of Yeast Genetics, Gamle Carlsberg Vej 10, DK-1799, Copenhagen V, Denmark.
Elisabetta MarchegianiEvolution and Genomics of Plant Pathogen Interactions, UR 1290 INRA, BIOGER-CPP, Campus AgroParisTech, 78850 Thiverval-Grignon, France.
Pankaj Vinod MehrotraAberdeen Fungal Group, School of Medical Sciences, Institute of Medical Sciences, University of Aberdeen, Aberdeen, UK.
Marino MorettiMax-Planck-Institute for Terrestrial Microbiology, Department of Organismic Interactions, Karl-von-Frisch-Strasse 10, D-35043 Marburg, Germany.
Vikram NaikMax-Planck-Institute for Terrestrial Microbiology, Department of Organismic Interactions, Karl-von-Frisch-Strasse 10, D-35043 Marburg, Germany.
Miriam Oses-RuizSchool of Biosciences, Geoffrey Pope Building, University of Exeter, Exeter EX4 4QD, UK.
Therese OskarssonCarlsberg Laboratory, Department of Yeast Genetics, Gamle Carlsberg Vej 10, DK-1799, Copenhagen V, Denmark.
Katja SchäferDepartment of Genetics, Edificio Gregor Mendel, Planta 1. Campus de Rabanales, University of Cordoba, 14071 Cordoba, Spain.
Lisa WasserstromCarlsberg Laboratory, Department of Yeast Genetics, Gamle Carlsberg Vej 10, DK-1799, Copenhagen V, Denmark.
Axel A BrakhageDepartment of Molecular and Applied Microbiology, Leibniz Institute for Natural Product Research and Infection Biology - Hans Knöll Institute (HKI), Beutembergstr. 11a, 07745 Jena, Germany; Department of Microbiology and Molecular Biology, Institute of Microbiology, Friedrich Schiller University Jena, Beutenbergstr. 11a, 07745 Jena, Germany.
Neil A R GowAberdeen Fungal Group, School of Medical Sciences, Institute of Medical Sciences, University of Aberdeen, Aberdeen, UK.
Regine KahmannMax-Planck-Institute for Terrestrial Microbiology, Department of Organismic Interactions, Karl-von-Frisch-Strasse 10, D-35043 Marburg, Germany.
Marc-Henri LebrunEvolution and Genomics of Plant Pathogen Interactions, UR 1290 INRA, BIOGER-CPP, Campus AgroParisTech, 78850 Thiverval-Grignon, France.
José Perez-MartinInstituto de Biología Funcional y GenómicaCSIC, Universidad de Salamanca, 37007 Salamanca, Spain.
Antonio Di PietroDepartment of Genetics, Edificio Gregor Mendel, Planta 1. Campus de Rabanales, University of Cordoba, 14071 Cordoba, Spain.
Nicholas J TalbotSchool of Biosciences, Geoffrey Pope Building, University of Exeter, Exeter EX4 4QD, UK.
Valerie ToquinBiochemistry Department, Bayer SAS, Bayer CropScience, CRLD, 69263 Lyon, France.
Andrea WaltherCarlsberg Laboratory, Department of Yeast Genetics, Gamle Carlsberg Vej 10, DK-1799, Copenhagen V, Denmark.
Jürgen WendlandCarlsberg Laboratory, Department of Yeast Genetics, Gamle Carlsberg Vej 10, DK-1799, Copenhagen V, Denmark.
Carlsberg Laboratory · DKUniversity of Córdoba · ESMax Planck Institute for Terrestrial Microbiology · DEUniversity of Aberdeen · GBAgroParisTech · FRInstituto de Biología Funcional y Genómica · ESLeibniz-Institut für Naturstoff-Forschung und Infektionsbiologie e. V. - Hans-Knöll-Institut (HKI) · DEUniversity of Exeter · GBBayer (Germany) · DECentre National de la Recherche Scientifique · FR

Funding

Wellcome Trust 101873
6 · The paper itself

Abstract

Fungi have the capacity to cause devastating diseases of both plants and animals, causing significant harvest losses that threaten food security and human mycoses with high mortality rates. As a consequence, there is a critical need to promote development of new antifungal drugs, which requires a comprehensive molecular knowledge of fungal pathogenesis. In this review, we critically evaluate current knowledge of seven fungal organisms used as major research models for fungal pathogenesis. These include pathogens of both animals and plants; Ashbya gossypii, Aspergillus fumigatus, Candida albicans, Fusarium oxysporum, Magnaporthe oryzae, Ustilago maydis and Zymoseptoria tritici. We present key insights into the virulence mechanisms deployed by each species and a comparative overview of key insights obtained from genomic analysis. We then consider current trends and future challenges associated with the study of fungal pathogenicity.

Indexed as

Chromosomes, FungalGenome, FungalFungiMitogen-Activated Protein Kinase KinasesSecondary MetabolismVirulenceMitogen-Activated Protein Kinase KinasesFungal model organismGenomicsHuman fungal pathogenPlant fungal pathogenVirulence

Identifiers

PMID25011008
PMCPMC4161391
OpenAlexW2045084922

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.