ArticleBrain research2014
Resting state alpha frequency is associated with menstrual cycle phase, estradiol and use of oral contraceptives.
Article in Brain research, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02214550 (Deciphering the Hormonal and Nociceptive Mechanisms Underlying Bladder Pain), which is not on this map. Cited by 50 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Deciphering the Hormonal and Nociceptive Mechanisms Underlying Bladder Pain
Who cites it
50 citing papers in PubMed, 2 syntheses or guidelines pooled it, 93 citations in OpenAlex.
- A systematic review of resting-state EEG across the menstrual cycle and its mental health relevance.Archives of women's mental health · 2026Pooled it
- Hormonal contraceptives and the brain: A systematic review on 60 years of neuroimaging, EEG, and biochemical studies in humans and animals.Frontiers in neuroendocrinology · 2023Pooled it
- Peak Alpha Frequency Is Not Significantly Altered by Five Days of Experimental Pain and Repetitive Transcranial Stimulation of the Left Dorsolateral Prefrontal Cortex.The European journal of neuroscience · 2025Trial
- One-week escitalopram intake alters the excitation-inhibition balance in the healthy female brain.Human brain mapping · 2022Trial
- Neural Oscillatory and Sympathetic Arousal Dynamics During Mindfulness Meditation: Characterizing Relaxed Alertness.Psychophysiology · 2026Article
- Neurofeedback, Biofeedback, and Basic Learning Theory: Revisiting the 2011 Conceptual Framework.Applied psychophysiology and biofeedback · 2026Review
- Contextual Modulation of Fronto-Central, Parietal, and Global Peak Alpha Frequency.European journal of pain (London, England) · 2026Article
- Mechanisms Underlying Pain Avoidance in Complex Regional Pain Syndrome.European journal of pain (London, England) · 2026Observational
- Association of widespread pain and peak alpha frequency cannot be isolated to a single network.Pain reports · 2026Article
- Hormonal contraceptives and EEG biomarkers for antidepressant treatment response in women.Communications medicine · 2026Article
- Altered cortical alpha modulations and connectivity in complex regional pain syndrome.The journal of pain · 2026Article
- Differential Impacts of Fronto-Cerebellar tACS and tVNS on Motor Learning: Evidence for Sex-Related Neural Modulation.Neural plasticity · 2026Article
- Sex differences in resting state EEG spectral power are more prominent than menstrual cycle effects in healthy young adults.Frontiers in endocrinology · 2026Article
- Individual stability of single-channel EEG measures over one year in healthy adults.Scientific reports · 2025Article
- Article
- Peak alpha frequency is related to the degree of widespread pain, but not pain intensity or duration, among people with urologic chronic pelvic pain syndrome.Pain reports · 2025Article
- Article
- Brain flexibility increases during the peri-ovulatory phase as compared to early follicular phase of the menstrual cycle.Scientific reports · 2024Article
- Brain fingerprint and subjective mood state across the menstrual cycle.Frontiers in neuroscience · 2024Article
- Changes in high-frequency aperiodic 1/f slope and periodic activity reflect post-stimulus functional inhibition in the visual cortex.Imaging neuroscience (Cambridge, Mass.) · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 2 countries.
Funding
Abstract
Ongoing intrinsic brain activity in resting, but awake humans is dominated by alpha oscillations. In human, individual alpha frequency (IAF) is associated with cognitive performance. Noticeable, performance in cognitive and emotional tasks in women is associated with menstrual cycle phase and sex hormone levels, respectively. In the present study, we correlated frequency of alpha oscillation in resting women with menstrual cycle phase, sex hormone level, or use of oral contraceptives. Electroencephalogram (EEG) was recorded from 57 women (aged 24.07 ± 3.67 years) having a natural menstrual cycle as well as from 57 women (aged 22.37 ± 2.20 years) using oral contraceptives while they sat in an armchair with eyes closed. Alpha frequency was related to the menstrual cycle phase. Luteal women showed highest and late follicular women showed lowest IAF or center frequency. Furthermore, IAF as well as center frequency correlated negatively with endogenous estradiol level, but did not reveal an association with endogenous progesterone. Women using oral contraceptives showed an alpha frequency similar to women in the early follicular phase. We suggest that endogenous estradiol modulate resting alpha frequency.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.