Evidence map›Paper›PMID 25010217›Full record

ReviewCurrent opinion in pediatrics2014

Pediatric inflammatory bowel disease and depression: treatment implications.

Divya Keethy, Christine Mrakotsky, Eva Szigethy

Open access · greenAbstract readReview
In one paragraph

Review in Current opinion in pediatrics, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 1 pooled it
4.8field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 1 synthesis or guideline pooled it, 39 citations in OpenAlex.

  1. Pooled it
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  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
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  11. Article
  12. Depression, anxiety, and loneliness among adolescents and young adults with IBD in the UK: the role of disease severity, age of onset, and embarrassment of the condition.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2021
    Article
  13. Article
  14. Article
  15. Inflammatory Bowel Disease in Childhood and Adolescence.Deutsches Arzteblatt international · 2017
    Review
  16. Review
  17. Article
  18. Article
  19. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 1 country.

Divya KeethyaUniversity of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania bDepartment of Psychiatry, Boston Children's Hospital, Boston, Massachusetts cDepartment of Psychiatry, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
Christine Mrakotsky
Eva Szigethy
Boston Children's Hospital · USChildren's Hospital of Pittsburgh · USUniversity of Pittsburgh · US

Funding

Reducing Depressive Symptoms in Physically Ill YouthR01MH077770 · NIMH · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI DEMASO, DAVID R, SZIGETHY, EVA M · 2008 to 2012
$3.2M
Corticosteroids, Inflammation, and Memory in Pediatric Inflammatory Bowel DiseaseK23HD058466 · NICHD · BOSTON CHILDREN'S HOSPITAL · PI MRAKOTSKY, CHRISTINE · 2008 to 2012
$794k
NICHD NIH HHS K23 HD058466NIMH NIH HHS R01 MH077770
6 · The paper itself

Abstract

purpose of reviewDepression in pediatric inflammatory bowel disease is increasingly recognized to be a heterogeneous condition with diverse underlying predisposing and precipitating factors. Although there is a growing awareness regarding the benefits of integrating behavioral health into medical care, the way psychiatric treatments can best target different aspects of depression and related dysfunction has not been systematically explored. RECENT

findingsThis review discusses neurobiological risk factors for depression in inflammatory bowel disease including inflammation, associated anti-inflammatory treatment with corticosteroids, pain, and sleep disturbance, as well as psychosocial factors including reactions to illness, illness perception, and disease and environmental stressors with an emphasis on how these factors can influence treatment decisions. Empirically supported psychosocial and psychopharmacological interventions are discussed within this context. SUMMARY: Understanding the diverse pathways that can lead to depression in youths with inflammatory bowel disease can lead to the development of more targeted interventions and better integration of psychosocial care into the medical treatment of inflammatory bowel disease.

Indexed as

Abdominal PainAdolescentAntidepressive AgentsChildChild, PreschoolCombined Modality TherapyDepressionHumansInflammationInflammatory Bowel DiseasesPsychophysiologic DisordersPsychotherapyRisk FactorsSleep Wake DisordersAntidepressive Agents

Identifiers

PMID25010217
PMCPMC4229361
OpenAlexW2319115568

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.