Evidence map›Paper›PMID 25010058›Full record

ArticlePloS one2014

Increased risk of acute coronary syndrome among patients with urinary stone disease: a nationwide population-based cohort study.

Shun-Fa Hung, Chao-Yuan Huang, Cheng-Li Lin, Shiu-Dong Chung, Chi-Jung Chung, Chia-Hung Kao, Chao-Hsiang Chang

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in PloS one, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 90% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 3 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Shun-Fa HungDivision of Urology, Department of Surgery, Far Eastern Memorial Hospital, Ban Ciao, Taipei, Taiwan; Graduate Institute of Clinical Medicine, College of Medicine, Fu-Jen Catholic University, New Taipei, Taiwan.
Chao-Yuan HuangDepartment of Urology, National Taiwan University Hospital, Taipei, Taiwan.
Cheng-Li LinManagement Office for Health Data, China Medical University Hospital, Taichung, Taiwan; College of Medicine, China Medical University, Taichung, Taiwan.
Shiu-Dong ChungDivision of Urology, Department of Surgery, Far Eastern Memorial Hospital, New Taipei, Taiwan; School of Medicine, College of Medicine, Fu Jen Catholic University, Taipei, Taiwan; Department of Urology, Buddhist Tzu Chi General Hospital and Tzu Chi University, Hualien, Taiwan.
Chi-Jung ChungDepartment of Health Risk Management, College of Public Health, China Medical University, Taichung, Taiwan; Department of Medical Research, China Medical University Hospital, Taichung, Taiwan.
Chia-Hung KaoGraduate Institute of Clinical Medical Science and School of Medicine, College of Medicine, China Medical University, Taichung, Taiwan; Department of Nuclear Medicine and PET Center, China Medical University Hospital, Taichung, Taiwan.
Chao-Hsiang ChangCollege of Medicine, China Medical University, Taichung, Taiwan; Department of Urology, China Medical University and Hospital, Taichung, Taiwan.
China Medical University · TWBuddhist Tzu Chi General Hospital · TWFu Jen Catholic University · TWNational Taiwan University Hospital · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

objectivesUrinary stones (US) are associated with systemic metabolic and endocrine disorders that share risk factors typically associated with acute coronary syndrome (ACS).

methodsFor this investigation, 30,142 patients with US were set as the research group, and 121,768 randomly selected patients were set as the comparison group through frequency matching by age, sex, and index year. Each patient was individually tracked to identify those who developed ACS during the follow-up period. Cox proportional hazards regression and the Kaplan-Meier method were adopted to calculate the hazard ratios of ACS risk and plot the survival curve.

resultsOverall, 275 (13.4 per 10,000 person-y) and 736 events (9.1 per 10,000 person-y) were observed among patients in the research and comparison cohorts, respectively. The patients with US had a substantially lower ACS-free survival rate compared with that of the patients in the comparison cohort (P<.001). After adjusting for potential risk factors, the patients with US were observed to have a 1.22-fold higher risk of ACS compared with patients in the comparison cohort (95% confidence interval = 1.05-1.40, P<.001), particularly among younger patients.

conclusionsThe results indicate that US is associated with increased risk of developing ACS, particularly among young (≤ 49 years) and male adults. Future studies should examine the possible mechanisms of US-related ACS morbidity by conducting multicenter recruitment and measurements of laboratory data.

Indexed as

Acute Coronary SyndromeAdultAgedAge FactorsCohort StudiesDiabetes MellitusFemaleHumansHypertensionMaleMiddle AgedProportional Hazards ModelsRisk FactorsSex FactorsUric AcidUrinary CalculiUric Acid

Identifiers

PMID25010058
PMCPMC4092153
OpenAlexW2005874382

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.