ArticleIranian journal of otorhinolaryngology2014
Effects of Fish Oil Supplementation during the Suckling Period on Auditory Neural Conduction in n-3 Fatty Acid-Deficient Rat Pups.
Article in Iranian journal of otorhinolaryngology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
2 citing papers in PubMed.
- Omega-3 fatty acids and health of auditory and vestibular systems: a comprehensive review.European journal of nutrition · 2024Review
- Dietary omega-3 polyunsaturated fatty acids reduce cytochrome c oxidase in brain white matter and sensorimotor regions while increasing functional interactions between neural systems related to escape behavior in postpartum rats.Frontiers in systems neuroscience · 2024Article
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Authors and funding
5 authors.
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Abstract
introductionOmega-3 fatty acid, particularly in the form of fish oil, has a structural and biological role in various systems of the body. The auditory and nervous systems are both influenced by omega-3 fatty acids, with omega-3 deficiency having devastating effects on both systems. Numerous studies have attempted to investigate this further. This study aimed to evaluate neural conduction in n-3 fatty acid-deficient rat pups following supplementation with fish oil during the suckling period. MATERIALS AND
methodsIn this interventional and experimental study, omega-3 fatty acids from fish oil (FO) were fed to rat pups of n-3 polyunsaturated fatty acid (PUFA)-deficient dams. Changes in auditory neural conduction were compared with those of control and n-3 PUFA-deficient groups using auditory brainstem response (ABR). The parameters of interest were P1, P3, and P4 absolute latency, P1-P3, P1-P4, and P3-P4 interpeak latency (IPL), and P4/P1 amplitude ratio. The rat pups were given oral FO, 5 ml/g weight for 17 days, between the age of 5 and 21 days.
resultsNo significant group differences were observed in P1 and P3 absolute latency (P>0.05), but there was a significant difference in P4 (P≤0.05). The n-3 PUFA-deficient + vehicle group had the most prolonged (the worst) P1-P4 IPL and P3-P4 IPL compared with control and n-3 PUFA-deficient + FO groups. There was no significant difference in P1-P4 IPL and P3-P4 IPL between the n-3 PUFA-deficient + FO group and the control group (P>0.05). There was a significant effect of diet on P1-P4 IPL and P3-P4 IPL between groups (P≤0.05).
conclusionThe results of present study showed the effect of omega-3 deficiency on auditory neural structure during pregnancy and the lactation period. Additionally, we observed reduced reduction in devastating effects on neural conduction in n-3 fatty acid-deficient rat pups following the supplementation of FO during the suckling period.
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25009803PMC4087852What OpenQuestion holds
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