Evidence map›Paper›PMID 25009761›Full record

ArticleJournal of nanomedicine & nanotechnology2014

Engineering of Nanoscale Contrast Agents for Optical Coherence Tomography.

Andrew Y Gordon, Ashwath Jayagopal

Open access · hybridAbstract read
In one paragraph

Article in Journal of nanomedicine & nanotechnology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.2field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Andrew Y GordonDepartment of Molecular Physiology and Biophysics, Vanderbilt University Medical Center, USA.
Ashwath JayagopalDepartment of Molecular Physiology and Biophysics, Vanderbilt University Medical Center, USA ; Vanderbilt Eye Institute, Vanderbilt University Medical Center, USA.
Vanderbilt University Medical Center · US

Funding

In Vivo Molecular Imaging of the RetinaR01EY023397 · NEI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI PENN, JOHN S., UDDIN, MD IMAM · 2013 to 2022
$3.6M
NEI NIH HHS R01 EY023397
6 · The paper itself

Abstract

Optical coherence tomography has emerged as valuable imaging modalityin ophthalmology and other fields by enabling high-resolution three-dimensional imaging of tissue. In this paper, we review recent progress in the field of contrast-enhanced optical coherence tomography (OCT). We discuss exogenous and endogenous sources of OCT contrast, focusing on their use with standard OCT systems as well as emerging OCT-based imaging modalities. We include advances in the processing of OCT data that generate improved tissue contrast, including spectroscopic OCT (SOCT), as well as work utilizing secondary light sources and/or detection mechanisms to create and detect enhanced contrast, including photothermal OCT (PTOCT) and photoacoustic OCT (PAOCT). Finally, we conclude with a discussion of the translational potential of these developments as well as barriers to their clinical use.

Identifiers

PMID25009761
PMCPMC4083612
OpenAlexW2038882375

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.