Evidence map›Paper›PMID 25009709›Full record

ArticleProceedings of SPIE--the International Society for Optical Engineering2014

Volume Holographic Reflection Endoscope for In-Vivo Ovarian Cancer Clinical Studies.

I D Howlett, M Gordon, J W Brownlee, J K Barton, R K Kostuk

Abstract read
In one paragraph

Article in Proceedings of SPIE--the International Society for Optical Engineering, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.0field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

I D HowlettPhotonic Systems Lab; Department of Electrical and Computer Engineering, University of Arizona, Tucson, AZ 85721 ; College of Optical Science, University of Arizona, Tucson, AZ 85721.
M GordonPhotonic Systems Lab; Department of Electrical and Computer Engineering, University of Arizona, Tucson, AZ 85721 ; College of Optical Science, University of Arizona, Tucson, AZ 85721.
J W BrownleePhotonic Systems Lab; Department of Electrical and Computer Engineering, University of Arizona, Tucson, AZ 85721 ; College of Optical Science, University of Arizona, Tucson, AZ 85721.
J K BartonCollege of Optical Science, University of Arizona, Tucson, AZ 85721 ; Biomedical Engineering, University of Arizona, Tucson, AZ 85721.
R K KostukPhotonic Systems Lab; Department of Electrical and Computer Engineering, University of Arizona, Tucson, AZ 85721 ; College of Optical Science, University of Arizona, Tucson, AZ 85721.
University of Arizona · US

Funding

A Spatial-Spectral Volume Holographic Imaging System for Ex-Vivo and In-Vivo CancR01CA134424 · NCI · UNIVERSITY OF ARIZONA · PI KOSTUK, RAYMOND K · 2009 to 2013
$2.0M
NCI NIH HHS R01 CA134424
6 · The paper itself

Abstract

We present the design for an endoscopic system capable of imaging tissues of the ovary at two selected imaging depths simultaneously. The method utilizes a multiplexed volume hologram to select wavefronts from different depths within the tissue. It is the first demonstration of an endoscopic volume holographic imaging system. The endoscope uses both gradient index (GRIN) optical components and off the shelf singlet lenses to relay an image from the distal tip to the proximal end. The endoscope has a minimum diameter of 3.75 mm. The system length is 30 cm which is connected to a handle that includes the holographic components and optics that relay the image to a camera. Preliminary evaluation of the endoscope was performed with tissue phantoms and calibrated targets, which shows lateral resolution ≈ 4 μm at an operating wavelength of 660 nm. The hologram is recorded in phenanthraquinone doped poly methacrylate and is designed to produce images from two tissue depths. One image is obtained at the tissue surface and the second 70 μm below the surface. This method requires no mechanical scanning and acquires an image at the camera frame rate. The preliminary ex-vivo results show good correlation with histology sections of the same tissue sections.

Indexed as

EndoscopyGRINOvarian Cancervolume holography

Identifiers

PMID25009709
PMCPMC4085110
OpenAlexW2055910866

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.