Evidence map›Paper›PMID 25009662›Full record

ArticleOncology letters2014

Correlation of CD146 expression and clinicopathological characteristics in esophageal squamous cell carcinoma.

Yan Li, Jin-Ming Yu, Xue-Mei Zhan, Li-Li Liu, Ning Jin, Yan-Xia Zhang

Open access · diamondAbstract read
In one paragraph

Article in Oncology letters, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
0.7field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 14 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Mel-CAM Expression in Common Oral Carcinomas.Journal of dentistry (Shiraz, Iran) · 2020
    Article
  4. Article
  5. Review
  6. Article
  7. Prognostic value of melanoma cell adhesion molecule expression in cancers: a meta-analysis.International journal of clinical and experimental medicine · 2015
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Yan LiDepartment of Radiation Oncology, Shandong Cancer Hospital, Shandong University, Jinan, Shandong 250117, P.R. China ; Department of Radiation Oncology, Linyi People's Hospital, Linyi, Shandong 276000, P.R. China.
Jin-Ming YuDepartment of Radiation Oncology, Shandong Cancer Hospital, Shandong University, Jinan, Shandong 250117, P.R. China.
Xue-Mei ZhanDepartment of Pathology, Linyi People's Hospital, Linyi, Shandong 276000, P.R. China.
Li-Li LiuDepartment of Pathology, Linyi People's Hospital, Linyi, Shandong 276000, P.R. China.
Ning JinDepartment of Pathology, Linyi People's Hospital, Linyi, Shandong 276000, P.R. China.
Yan-Xia ZhangDepartment of Radiation Oncology, Linyi People's Hospital, Linyi, Shandong 276000, P.R. China.
Linyi People's Hospital · CNShandong University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

CD146, a cell adhesion molecule, is found in normal and tumor tissues. The level of its expression has been found to directly correlate with tumor progression and metastatic potential. The objective of this study was to investigate the expression of CD146 in esophageal squamous cell carcinoma (ESCC) and its correlation with clinicopathological parameters. Tumor specimens were collected from 63 patients with ESCC who underwent complete resection. We analyzed the CD146 expression levels in ESCC by immunohistochemistry. The expression of CD146 was detected and it was observed to correlate with clinicopathological parameters. Sixty-three cases of normal squamous mucosa were included for comparison. CD146 expression was identified in 46.0% (29/63) of the ESCC samples, and no positive (weak to moderate or moderate to strong) expression was found in the normal squamous epithelium samples (χ

Indexed as

CD146clinicopathological characteristicsesophageal squamous cell cancerimmunohistochemistry

Identifiers

PMID25009662
PMCPMC4081421
OpenAlexW2082656136

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.