ArticleExperimental and therapeutic medicine2014
Red cell distribution width predicts short- and long-term outcomes of acute congestive heart failure more effectively than hemoglobin.
Article in Experimental and therapeutic medicine, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed.
- Longitudinal Changes in Hematological Status and Functional Capacity During Hospitalization Are Associated With Clinical Outcomes in Older Patients With Acute Decompensated Heart Failure.Circulation reports · 2026Article
- Hemoglobin-to-Red Cell Distribution Width Ratio as a Prognostic Marker in Decompensated Heart Failure Patients: A Prospective Observational Study.Life (Basel, Switzerland) · 2026Article
- Association Between Red Blood Cell Distribution width and Long-Term Mortality in Patients with Intracerebral Hemorrhage.Neurocritical care · 2024Article
- Assessing red blood cell distribution width in Vietnamese heart failure patients: A cross-sectional study.PloS one · 2024Article
- In-hospital changes in the red blood cell distribution width and mortality in critically ill patients with heart failure.ESC heart failure · 2023Article
- Red blood cell distribution width and all-cause mortality in congestive heart failure patients: a retrospective cohort study based on the Mimic-III database.Frontiers in cardiovascular medicine · 2023Article
- Red Blood Cell Distribution Width in Heart Failure: Pathophysiology, Prognostic Role, Controversies and Dilemmas.Journal of clinical medicine · 2022Review
- Red Blood Cell Distribution Width as Novel Biomarker in Cardiovascular Diseases: A Literature Review.Journal of blood medicine · 2022Review
- Red Cell Distribution Width as a Marker of Periprocedural Myocardial Infarction in Patients with Elective Percutaneous Coronary Intervention.Journal of cardiovascular translational research · 2021Article
- Article
- Ancestry-specific associations identified in genome-wide combined-phenotype study of red blood cell traits emphasize benefits of diversity in genomics.BMC genomics · 2020Article
- A Predictive Model for Acute Respiratory Distress Syndrome Mortality Using Red Cell Distribution Width.Critical care research and practice · 2020Article
- Prognostic significance of red cell distribution width and its relation to increased pulmonary pressure and inflammation in acute heart failure.Cardiology journal · 2020Article
- Full blood count as potential predictor of outcomes in patients undergoing cardiac resynchronization therapy.Scientific reports · 2019Article
- Red Blood Cell Distribution Width Improves Reclassification of Patients Admitted to the Emergency Department with Acute Decompensated Heart Failure.Journal of medical biochemistry · 2018Article
- Red Blood Cell Distribution Width: A Novel Predictive Indicator for Cardiovascular and Cerebrovascular Diseases.Disease markers · 2017Review
- Observational
- Red blood cell distribution width and cardiovascular diseases.Journal of thoracic disease · 2015Review
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The present study compared short- and long-term prognostic values of red blood cell distribution width (RDW) with those of hemoglobin (Hgb) among patients with acute congestive heart failure (CHF) in a cardiac care unit. The cross-sectional study examined data from 521 patients with acute CHF who were admitted to a cardiac care unit and followed up for 24 months (median). Mean Hgb levels in patients who succumbed (DIH) or remained alive (AIH) were 11.0±1.8 and 11.8±2.6 g/l (P>0.05), respectively. Median values of RDW were 16.2% and 14.4%, respectively (P<0.0001). During the 24-month follow-up, mean levels of Hgb in groups with and without endpoints were 11.4±2.5 and 12.5±2.4 g/dl (P<0.0001), respectively. Median RDW values were 14.9 and 13.8%, respectively (P<0.0001). Logistic regression analysis showed that in-hospital mortality was significantly associated with RDW (P=0.044), New York Heart Association (NYHA) functional class IV (P=0.0037), estimated glomerular filtration rate (eGFR) (P=0.042) and C-reactive protein (P=0.0044), but not with Hgb (P=0.10). The multivariate Cox proportional hazard model selected RDW [hazard ratio (HR), 2.19; P<0.0001], left ventricular ejection fraction (HR 0.81, P=0.0016), age (10-year increase; HR 1.19, P=0.0017) and NYHA functional classes III/IV (HR 1.52, P=0.0029) as independent predictors of long-term outcomes after adjustment, but not Hgb (HR 1.01, P=0.86). Higher RDW values in acute CHF patients at admission were associated with worse short- and long-term outcomes and RDW values were more prognostically relevant than Hgb levels.
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