Evidence map›Paper›PMID 25009582›Full record

ArticleExperimental and therapeutic medicine2014

IFN-γ mediates graft-versus-breast cancer effects via enhancing cytotoxic T lymphocyte activity.

Qianjie Zhao, Lingling Tong, Ningning He, Guowei Feng, Liang Leng, Weijun Sun, Yang Xu, Yuebing Wang, Rong Xiang, Zongjin Li

Open access · diamondAbstract read
In one paragraph

Article in Experimental and therapeutic medicine, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.3field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Article
  3. Allogeneic Mouse Models of Graft-Versus-Host Disease.Methods in molecular biology (Clifton, N.J.) · 2025
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  4. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Qianjie ZhaoDepartment of Pathophysiology, School of Medicine, Nankai University, Ministry of Education, Tianjin 300071, P.R. China ; Key Laboratory of Bioactive Materials, College of Life Science, Nankai University, Ministry of Education, Tianjin 300071, P.R. China.
Lingling TongDepartment of Pathophysiology, School of Medicine, Nankai University, Ministry of Education, Tianjin 300071, P.R. China.
Ningning HeDepartment of Pathophysiology, School of Medicine, Nankai University, Ministry of Education, Tianjin 300071, P.R. China.
Guowei FengDepartment of Pathophysiology, School of Medicine, Nankai University, Ministry of Education, Tianjin 300071, P.R. China.
Liang LengDepartment of Pathophysiology, School of Medicine, Nankai University, Ministry of Education, Tianjin 300071, P.R. China.
Weijun SunDepartment of Pathophysiology, School of Medicine, Nankai University, Ministry of Education, Tianjin 300071, P.R. China.
Yang XuDepartment of Pathophysiology, School of Medicine, Nankai University, Ministry of Education, Tianjin 300071, P.R. China.
Yuebing WangDepartment of Pathophysiology, School of Medicine, Nankai University, Ministry of Education, Tianjin 300071, P.R. China.
Rong XiangDepartment of Pathophysiology, School of Medicine, Nankai University, Ministry of Education, Tianjin 300071, P.R. China.
Zongjin LiDepartment of Pathophysiology, School of Medicine, Nankai University, Ministry of Education, Tianjin 300071, P.R. China ; Key Laboratory of Bioactive Materials, College of Life Science, Nankai University, Ministry of Education, Tianjin 300071, P.R. China.
Nankai University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Previous studies have demonstrated the beneficial effect of graft-versus-tumor (GVT) following hematopoietic stem cell transplantation (HSCT) on the incidence of leukemia relapse and the overall survival rate of patients with leukemia; however, detailed mechanisms underlying the effects GVT exhibits on solid tumors following allogeneic HSCT are yet to be elucidated. The aim of the present study was to investigate the immune mechanism underlying the effect of interferon (IFN)-γ on GVT following allogeneic HSCT in breast cancer therapy. An

Indexed as

breast cancercytotoxic T lymphocytesgraft-versus-tumorgranzyme Binterferon-γ

Identifiers

PMID25009582
PMCPMC4079438
OpenAlexW2091939066

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.