ArticleProceedings of the National Academy of Sciences of the United States of America2014
Intracellular Ca-carbonate biomineralization is widespread in cyanobacteria.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 54 papers.
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Who cites it
54 citing papers in PubMed, 243 citations in OpenAlex.
- Targeted genome editing of the non-model cyanobacterium Cyanothece PCC 7425 via CRISPR/Cas12a.Applied microbiology and biotechnology · 2026Article
- Ecological, Functional, and Phylogenetic Determinants of Cyanobacterial Biomineralisation.Environmental microbiology reports · 2026Review
- Applications of bio-enhanced cementitious composites for sustainable building materials: emission-reduction and carbon-sequestration pathways.Systems microbiology and biomanufacturing · 2026Review
- The Role of Confinement in Biomineralization.Chemical reviews · 2025Review
- Deep-branching magnetotactic bacteria form intracellular carbonates enriched in trace metals.mSystems · 2025Article
- Calcite precipitation by the nitrogen-fixing cyanobacterium Anabaena sp. ATCC 33047.Communications biology · 2025Article
- Comparing Protein Stability in Modern and Ancient Sabkha Environments: Implications for Molecular Remnants on Ancient Mars.International journal of molecular sciences · 2025Article
- Magnetotactic bacteria affiliated with diverse Pseudomonadota families biomineralize intracellular Ca-carbonate.The ISME journal · 2025Article
- Hard shell, soft blue-green core: Ecology, processes, and modern applications of calcification in terrestrial cyanobacteria.iScience · 2024Review
- Chemical and Acoustical Mixed-Mapping of Geological Materials from Laser-Induced Plasmas: A Comprehensive Approach to Differentiate Mineral Phases.Analytical chemistry · 2024Article
- Abiotic and biotic-controlled nanomaterial formation pathways within the Earth's nanomaterial cycle.Communications earth & environment · 2024Review
- Microbial functionalities and immobilization of environmental lead: Biogeochemical and molecular mechanisms and implications for bioremediation.Journal of hazardous materials · 2023Review
- Will tomorrow's mineral materials be grown?Microbial biotechnology · 2023Article
- A re-examination of the mechanism of whiting events: A new role for diatoms in Fayetteville Green Lake (New York, USA).Geobiology · 2023Article
- High calcium and strontium uptake by the green microalga Tetraselmis chui is related to micropearl formation and cell growth.Environmental microbiology reports · 2023Article
- Deep resilience: An evolutionary perspective on calcification in an age of ocean acidification.Frontiers in physiology · 2023Article
- Biodesalination using halophytic cyanobacterium Phormidium keutzingianum from brackish to the hypersaline water.Chemosphere · 2022Article
- Mineralogy of Bioprecipitate Evolution over Induction Times Mediated by Halophilic Bacteria under Various Mg/Ca Molar Ratios.ACS omega · 2022Article
- The roles of intracellular and extracellular calcium iniScience · 2022Article
- The oldest mineralized bryozoan? A possible palaeostomate in the lower Cambrian of Nevada, USA.Science advances · 2022Article
Corrections and comments
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Authors and funding
14 authors at 7 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Cyanobacteria have played a significant role in the formation of past and modern carbonate deposits at the surface of the Earth using a biomineralization process that has been almost systematically considered induced and extracellular. Recently, a deep-branching cyanobacterial species, Candidatus Gloeomargarita lithophora, was reported to form intracellular amorphous Ca-rich carbonates. However, the significance and diversity of the cyanobacteria in which intracellular biomineralization occurs remain unknown. Here, we searched for intracellular Ca-carbonate inclusions in 68 cyanobacterial strains distributed throughout the phylogenetic tree of cyanobacteria. We discovered that diverse unicellular cyanobacterial taxa form intracellular amorphous Ca-carbonates with at least two different distribution patterns, suggesting the existence of at least two distinct mechanisms of biomineralization: (i) one with Ca-carbonate inclusions scattered within the cell cytoplasm such as in Ca. G. lithophora, and (ii) another one observed in strains belonging to the Thermosynechococcus elongatus BP-1 lineage, in which Ca-carbonate inclusions lie at the cell poles. This pattern seems to be linked with the nucleation of the inclusions at the septum of the cells, showing an intricate and original connection between cell division and biomineralization. These findings indicate that intracellular Ca-carbonate biomineralization by cyanobacteria has been overlooked by past studies and open new perspectives on the mechanisms and the evolutionary history of intra- and extracellular Ca-carbonate biomineralization by cyanobacteria.
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