ArticleLipids in health and disease2014
Multivessel coronary artery disease, free fatty acids, oxidized LDL and its antibody in myocardial infarction.
Article in Lipids in health and disease, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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19 citing papers in PubMed, 36 citations in OpenAlex.
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- Correlation of Lp(a), ApoB and oxLDL with Endothelial Damage Reading in Patients with Different Degrees of Coronary Atherosclerosis.International journal of molecular sciences · 2026Article
- Association Between Blood Free Fatty Acid Concentrations in Midlife and Cerebral Small Vessel Disease.Antioxidants (Basel, Switzerland) · 2025Article
- The Dual Role of Oxidative Stress in Atherosclerosis and Coronary Artery Disease: Pathological Mechanisms and Diagnostic Potential.Antioxidants (Basel, Switzerland) · 2025Review
- Overview of Clinical Relevance of Antibodies Against Oxidized Low-Density Lipoprotein (oLAb) Within Three Decades by ELISA Technology.Antioxidants (Basel, Switzerland) · 2024Review
- Breaking tolerance: the autoimmune aspect of atherosclerosis.Nature reviews. Immunology · 2024Review
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- Protein lysine acetylation does not contribute to the high rates of fatty acid oxidation seen in the post-ischemic heart.Scientific reports · 2024Article
- Predicting Diagnostic Gene Biomarkers Associated With Immune Infiltration in Patients With Acute Myocardial Infarction.Frontiers in cardiovascular medicine · 2020Article
- Anti-Oxidized LDL Antibodies and Coronary Artery Disease: A Systematic Review.Antioxidants (Basel, Switzerland) · 2019Review
- Associations between circulating IgG antibodies to Apolipoprotein BBioscience reports · 2018Article
- Article
- Oxidative Modification of LDL by Various Physicochemical Techniques: Its Probable Role in Diabetes Coupled with CVDs.BioMed research international · 2018Article
- A Novel Y-Specific Long Non-Coding RNA Associated with Cellular Lipid Accumulation in HepG2 cells and Atherosclerosis-related Genes.Scientific reports · 2017Article
- Apolipoprotein A1 polymorphisms and risk of coronary artery disease: a meta-analysis.Archives of medical science : AMS · 2017Article
- Free fatty acids and cardiovascular outcome: a Chinese cohort study on stable coronary artery disease.Nutrition & metabolism · 2017Article
- Effect of apolipoprotein A1 genetic polymorphisms on lipid profiles and the risk of coronary artery disease.Diagnostic pathology · 2015Article
- Detection of circulating IgG antibodies to apolipoprotein B100 in acute myocardial infarction.FEBS open bio · 2015Article
- Contribution of various lipid profile parameters in determining creatine kinase-MB levels in unstable angina patients.International journal of applied & basic medical researchArticle
Corrections and comments
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Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundFree fatty acids (FFA), oxidized low-density lipoprotein (LDL) and its antibodies, lipid profile markers, which are formed under oxidative stress, play an important role in atherosclerotic disease. Assess the levels of these markers in myocardial infarction patients depending on the extent of coronary artery disease (CAD).
methodsST-elevation MI patients with hemodynamically significant stenoses of ≥ 75% in one, two, three, or more coronary arteries were examined. The patients were divided into three groups according to the severity of coronary lesions. Patients had a ≥ 75% stenotic lesion in one coronary artery (group 1, n=135), two coronary arteries (group 2, n=115), or three or more coronary arteries (group 3, n=150). The control group comprised healthy subjects (n=33).
resultsFFA levels on day 1 from MI onset were higher in groups 1, 2, and 3 compared with controls. On day 1 from MI onset, oxidized LDL levels were significantly higher in groups 2 and 3 than those in controls (both р=0.001). Oxidized LDL levels were significantly higher in patients with multivessel CAD compared with those with single-vessel CAD on days 1 and 12. Antibody levels increased with the number of affected arteries.
conclusionHigh levels FFA, oxidized LDL and its antibody, lipid profile markers, and parameters of the pro/antioxidant systems persist during the subacute phase of MI.
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