Unraveling the PAF-AH/Lp-PLA2 controversy.

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

Who cites it

17 citing papers in PubMed.

1. Divergent effects of PLA2G7 on prostate cancer biochemical recurrence in European American and African American men.Journal of the National Cancer Institute · 2026
   Article
2. Lipoprotein-associated phospholipase A2 (Lp-PLA2): a key hub linking lipid metabolism and immune inflammation.Frontiers in immunology · 2026
   Review
3. Lands' Cycle at the Crossroads: Phospholipid Remodelling, Oxidative Stress, Cellular Toxicity, and Therapeutic Targeting.ACS pharmacology & translational science · 2025
   Review
4. Phospholipase PLA2G7 is complementary to GPX4 in mitigating punicic-acid-induced ferroptosis in prostate cancer cells.iScience · 2024
   Article
5. Can Electronegative LDL Act as a Multienzymatic Complex?International journal of molecular sciences · 2023
   Review
6. A proteomic approach for investigating the pleiotropic effects of statins in the atherosclerosis risk in communities (ARIC) study.Journal of proteomics · 2023
   Article
7. Association of circulating PLA2G7 levels with cancer cachexia and assessment of darapladib as a therapy.Journal of cachexia, sarcopenia and muscle · 2021
   Article
8. Metabolic Dysregulation of the Lysophospholipid/Autotaxin Axis in the Chromosome 9p21 Gene SNP rs10757274.Circulation. Genomic and precision medicine · 2020
   Article
9. Forty Years Since the Structural Elucidation of Platelet-Activating Factor (PAF): Historical, Current, and Future Research Perspectives.Molecules (Basel, Switzerland) · 2019
   Review
10. Modulation of inflammatory platelet-activating factor (PAF) receptor by the acyl analogue of PAF.Journal of lipid research · 2018
    Article
11. Phospholipid signaling in innate immune cells.The Journal of clinical investigation · 2018
    Review
12. Inflammation, not Cholesterol, Is a Cause of Chronic Disease.Nutrients · 2018
    Review
13. The role of Lp-PLACardiovascular diagnosis and therapy · 2017
    Article
14. Hydrolysis of Phosphatidylcholine-Isoprostanes (PtdCho-IP) by Peripheral Human Group IIA, V and X Secretory Phospholipases ALipids · 2017
    Article
15. Bioactive Carbohydrates and Peptides in Foods: An Overview of Sources, Downstream Processing Steps and Associated Bioactivities.International journal of molecular sciences · 2015
    Review
16. Introduction to Thematic Review Series: Phospholipases: Central Role in Lipid Signaling and Disease.Journal of lipid research · 2015
    Article
17. SERUM LIPOPROTEIN-ASSOCIATED PHOSPHOLIPASE A2 IN MALES WITH METABOLIC SYNDROME AND OBSTRUCTIVE SLEEP APNEA.Acta endocrinologica (Bucharest, Romania : 2005)
    Article

Corrections and comments

• Comment on
  To hydrolyze or not to hydrolyze: the dilemma of platelet-activating factor acetylhydrolase.2014

Authors and funding

2 authors.

Funding

No grant is acknowledged in the PubMed record.

Abstract

PubMed holds no abstract for this paper.

Indexed as