Evidence map›Paper›PMID 25007735›Full record

ArticleEuropean archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery2015

Correlation between clinical findings and eosinophil/neutrophil ratio in patients with nasal polyps.

S Hancer Tecimer, F Kasapoglu, U L Demir, O A Ozmen, H Coskun, O Basut

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Article in European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Article
  2. Devils in the Details: Analysis of Detailed Histopathological Reporting of Tissue Samples in Primary Diffuse Chronic Rhinosinusitis-A Clinical and Pathological Perspective.Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India · 2025
    Article
  3. Article
  4. Eosinophilic and Non-eosinophilic Chronic Rhinosinusitis with Nasal Polyps and Their Clinical Comparison in Indian Population.Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India · 2022
    Article
  5. Article
  6. Aspirin Exacerbated Respiratory Disease and Nasal Polyp Phenotyping.Iranian journal of pharmaceutical research : IJPR · 2021
    Article
  7. Can the systemic immune inflammation index preoperatively predict nasal polyp subtypes?European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2020
    Article
  8. Computed Tomography Score an Excellent Marker: Differentiates Eosinophilic and Non-eosinophilic Variants of Chronic Rhinosinusitis with Nasal Polyp.Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India · 2019
    Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. Review
  14. Letter to the editor concerning: 'Correlation between clinical findings and eosinophil/neutrophil ratio in patients with nasal polyps'.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2016
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors.

S Hancer TecimerDepartment of Otolaryngology and Head and Surgery, Uludag University Medical School, 16059 Gorukle, Nilufer, Bursa, Turkey.
F KasapogluDepartment of Otolaryngology and Head and Surgery, Uludag University Medical School, 16059 Gorukle, Nilufer, Bursa, Turkey.
U L DemirDepartment of Otolaryngology and Head and Surgery, Uludag University Medical School, 16059 Gorukle, Nilufer, Bursa, Turkey. uygardemir@hotmail.com.
O A OzmenDepartment of Otolaryngology and Head and Surgery, Uludag University Medical School, 16059 Gorukle, Nilufer, Bursa, Turkey.
H CoskunDepartment of Otolaryngology and Head and Surgery, Uludag University Medical School, 16059 Gorukle, Nilufer, Bursa, Turkey.
O BasutDepartment of Otolaryngology and Head and Surgery, Uludag University Medical School, 16059 Gorukle, Nilufer, Bursa, Turkey.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chronic rhinosinusitis with nasal polyps (CRSwNP) is a frequent disease which can be classified as eosinophilic or neutrophilic based on dominant inflammatory cell type at tissue. The aim of this study was to evaluate the clinical relevance of classifying nasal polyps as eosinophilic or neutrophilic on treatment outcomes. The study was conducted with 40 patients who underwent either surgical or medical treatment with the diagnosis of CRSwNP. The patients were classified into two groups for further assessment up to eosinophil intensity at polyp tissue. All patients were examined by nasal endoscopy and paranasal computed tomography (CT). Before treatment, subjective symptom score, nasal endoscopy score, and CT score were measured. Subsequently, they were reevaluated by similar diagnostic tests after either medical or surgical treatment at sixth month. The preoperative subjective symptom score, endoscopy score, and paranasal CT score were compared between chronic rhinosinusitis (CRS) with eosinophilic nasal polyps (E-NP) (CRSwE-NP) group and CRS with neutrophilic nasal polyps group and there was no difference between the two groups (p = 0.369, p = 0.310 and p = 0.494 respectively). Although after treatment in both groups symptom score and endoscopy score were significantly improved but not the CT score, we found no difference in between the groups at sixth month. In most of the previous studies, patients with CRSwE-NP were assumed to have poor prognosis and high recurrence rate despite surgical or medical treatment. However, we did not find any association between eosinophilic or neutrophilic nature of nasal polyp tissue and disease severity.

Indexed as

Nasal PolypsRhinitisSinusitisAdultChronic DiseaseEndoscopyEosinophiliaEosinophilsFemaleHumansMaleNeutrophilsParanasal SinusesRetrospective StudiesTomography, X-Ray ComputedTreatment Outcome

Identifiers

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.