Evidence map›Paper›PMID 25007351›Full record

ArticleAnalytical chemistry2014

Glycan based detection and drug susceptibility of influenza virus.

Hieu Dinh, Xiaohu Zhang, Joyce Sweeney, Yang Yang, Yun He, Abasaheb Dhawane, Suri S Iyer

Abstract readEvaluation Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Analytical chemistry, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Surface-Controlled Sialoside-Based Biosensing of Viral and Bacterial Neuraminidases.Langmuir : the ACS journal of surfaces and colloids · 2024
    Article
  2. Article
  3. Review
  4. Glycan Array Technology.Advances in biochemical engineering/biotechnology · 2021
    Article
  5. Review
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Hieu Dinh788 Petit Science Center, Department of Chemistry, Center for Diagnostics and Therapeutics, Georgia State University , Atlanta, Georgia 30302, United States.
Xiaohu Zhang
Joyce Sweeney
Yang Yang
Yun He
Abasaheb Dhawane
Suri S Iyer

Funding

Receptor Mimics for Rapid Detection, Typing, and Susceptibility Testing of InflueR01AI089450 · NIAID · UNIVERSITY OF CINCINNATI · PI IYER, SURI SARANATHAN, WEISS, ALISON A. · 2010 to 2014
$2.2M
NIAID NIH HHS R01 AI089450NIAID NIH HHS R01-AI089450
6 · The paper itself

Abstract

We have developed a panel of synthetic glycans as receptor mimics for the specific capture of influenza viruses. The glycans were printed onto commercial glass slides using a free amine at the end of a spacer to generate a small focused microarray. The microarray was evaluated for its ability to capture three different strains of influenza A virus, two H1N1, A/Brisbane/59/2007 and A/Solomon Islands/3/2006 and one H3N2, A/Aichi/2/1968. We observed an excellent detection ability with some compounds exhibiting clinically relevant (10(1) plaque forming units) limit of detection. We also tested the drug susceptibility of current antivirals, Zanamivir and Ostelamivir using this microarray and could determine antiviral resistance for these strains.

Indexed as

Antiviral AgentsBiosensing TechniquesDrug Resistance, ViralHumansInfluenza A virusInfluenza A Virus, H1N1 SubtypeInfluenza A Virus, H3N2 SubtypeInfluenza, HumanLimit of DetectionMicroarray AnalysisMicrobial Sensitivity TestsOseltamivirPolysaccharidesZanamivirAntiviral AgentsOseltamivirPolysaccharidesZanamivir

Identifiers

PMID25007351
PMCPMC4139186

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.