ArticlePloS one2014
Interplay between short- and long-term plasticity in cell-assembly formation.
Article in PloS one, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed.
- A unified model of short- and long-term plasticity: Effects on network connectivity and information capacity.PLoS computational biology · 2026Article
- Predictive learning rules generate a cortical-like replay of probabilistic sensory experiences.eLife · 2025Article
- Biphasic Cholinergic Modulation of Reverberatory Activity in Neuronal Networks.Neuroscience bulletin · 2023Article
- Drifting assemblies for persistent memory: Neuron transitions and unsupervised compensation.Proceedings of the National Academy of Sciences of the United States of America · 2021Article
- Endogenous neurosteroids pregnanolone and pregnanolone sulfate potentiate presynaptic glutamate release through distinct mechanisms.British journal of pharmacology · 2021Article
- Disruption of Cholinergic Circuits as an Area for Targeted Drug Treatment of Alzheimer's Disease: In Vivo Assessment of Short-Term Plasticity in Rat Brain.Pharmaceuticals (Basel, Switzerland) · 2020Article
- Autonomous emergence of connectivity assemblies via spike triplet interactions.PLoS computational biology · 2020Article
- From Topological Analyses to Functional Modeling: The Case of Hippocampus.Frontiers in computational neuroscience · 2020Article
- Reduced presynaptic vesicle stores mediate cellular and network plasticity defects in an early-stage mouse model of Alzheimer's disease.Molecular neurodegeneration · 2019Article
- Replays of spatial memories suppress topological fluctuations in cognitive map.Network neuroscience (Cambridge, Mass.) · 2019Article
- Associative properties of structural plasticity based on firing rate homeostasis in recurrent neuronal networks.Scientific reports · 2018Article
- Estimating short-term synaptic plasticity from pre- and postsynaptic spiking.PLoS computational biology · 2017Article
- A Lognormal Recurrent Network Model for Burst Generation during Hippocampal Sharp Waves.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2015Article
- Mixed signal learning by spike correlation propagation in feedback inhibitory circuits.PLoS computational biology · 2015Article
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2 authors.
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Abstract
Various hippocampal and neocortical synapses of mammalian brain show both short-term plasticity and long-term plasticity, which are considered to underlie learning and memory by the brain. According to Hebb's postulate, synaptic plasticity encodes memory traces of past experiences into cell assemblies in cortical circuits. However, it remains unclear how the various forms of long-term and short-term synaptic plasticity cooperatively create and reorganize such cell assemblies. Here, we investigate the mechanism in which the three forms of synaptic plasticity known in cortical circuits, i.e., spike-timing-dependent plasticity (STDP), short-term depression (STD) and homeostatic plasticity, cooperatively generate, retain and reorganize cell assemblies in a recurrent neuronal network model. We show that multiple cell assemblies generated by external stimuli can survive noisy spontaneous network activity for an adequate range of the strength of STD. Furthermore, our model predicts that a symmetric temporal window of STDP, such as observed in dopaminergic modulations on hippocampal neurons, is crucial for the retention and integration of multiple cell assemblies. These results may have implications for the understanding of cortical memory processes.
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