Evidence map›Paper›PMID 25007160›Full record

ArticleMarine drugs2014

Nocapyrones: α- and γ-pyrones from a marine-derived Nocardiopsis sp.

Youngju Kim, Hiromu Ogura, Kazuaki Akasaka, Tsutomu Oikawa, Nobuyasu Matsuura, Chiaki Imada, Hisato Yasuda, Yasuhiro Igarashi

Abstract read
In one paragraph

Article in Marine drugs, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Polymer degrading marineBeilstein journal of organic chemistry · 2024
    Review
  5. Review
  6. Article
  7. Article
  8. Review
  9. GenusMarine drugs · 2022
    Review
  10. Synthetic study toward tridachiapyrone B.Beilstein journal of organic chemistry · 2022
    Article
  11. Review
  12. Article
  13. Review
  14. Two new aromatic polyketides from a sponge-derivedBeilstein journal of organic chemistry · 2019
    Article
  15. Article
  16. Review
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Youngju KimBiotechnology Research Center and Department of Biotechnology, Toyama Prefectural University, 5180 Kurokawa, Imizu, Toyama 939-0398, Japan. youngju.kim.c@gmail.com.
Hiromu OguraBiotechnology Research Center and Department of Biotechnology, Toyama Prefectural University, 5180 Kurokawa, Imizu, Toyama 939-0398, Japan. qqct6qc9k@blue.ocn.ne.jp.
Kazuaki AkasakaShokei Gakuin University, 4-10-1 Yurigaoka, Natori, Miyagi 981-1295, Japan. akasaka@shokei.ac.jp.
Tsutomu OikawaSchool of Nutrition and Dietetics, Kanagawa University of Human Services, 1-10-1 Heisei-cho, Yokosuka, Kanagawa 238-8566, Japan. oikawa-t@kuhs.ac.jp.
Nobuyasu MatsuuraOkayama University of Science, 1-1 Ridai-cho, Okayama, Okayama 700-0005, Japan. nobuyasu@dls.ous.ac.jp.
Chiaki ImadaTokyo University of Marine Science and Technology, 4-5-7 Konan, Minato-ku, Tokyo 108-8477, Japan. imada@kaiyodai.ac.jp.
Hisato YasudaCenter for Advanced Marine Core Research, Kochi University, B200 Monobe, Nankoku, Kochi 783-8502, Japan. yasuda@kochi-u.ac.jp.
Yasuhiro IgarashiBiotechnology Research Center and Department of Biotechnology, Toyama Prefectural University, 5180 Kurokawa, Imizu, Toyama 939-0398, Japan. yas@pu-toyama.ac.jp.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

One new α-pyrone (nocapyrone R (1)), and three known γ-pyrones (nocapyrones B, H and L (2-4)) were isolated from the culture extract of a Nocardiopsis strain collected from marine sediment. Structures of these compounds were determined on the basis of spectroscopic data including NMR and MS. γ-Pyrones 2-4 were found to induce adiponectin production in murine ST-13 preadipocyte cells but the α-pyrone 1 had no activity. The absolute configuration of the anteiso-methyl branching in 4 was determined by HPLC comparison of a degraded product of 4 with standard samples as a 2:3 enantiomeric mixture of (R)- and (S)-isomers.

Indexed as

ActinobacteriaMagnetic Resonance SpectroscopyPyronesPyrones

Identifiers

PMID25007160
PMCPMC4113818

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.