Evidence map›Paper›PMID 25007088›Full record

ReviewSeminars in respiratory and critical care medicine2014

Sarcoidosis-associated pulmonary hypertension and lung transplantation for sarcoidosis.

Michael Y Shino, Joseph P Lynch Iii, Michael C Fishbein, Charles McGraw, Jared Oyama, John A Belperio, Rajan Saggar

Open access · greenAbstract readReview
In one paragraph

Review in Seminars in respiratory and critical care medicine, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
3.5field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 44 citations in OpenAlex.

  1. Guideline
  2. Sarcoidosis-Associated Pulmonary Hypertension.Journal of clinical medicine · 2024
    Review
  3. Article
  4. Sarcoidosis-associated pulmonary fibrosis: joining the dots.European respiratory review : an official journal of the European Respiratory Society · 2023
    Review
  5. Article
  6. Article
  7. Article
  8. Ventilatory disturbances in patients with intrathoracic sarcoidosis - a study from a functional and histological perspective.Sarcoidosis, vasculitis, and diffuse lung diseases : official journal of WASOG · 2017
    Article
  9. Article
  10. [Sarcoidosis].Zeitschrift fur Rheumatologie · 2016
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Michael Y ShinoDivision of Pulmonary and Critical Care Medicine, Department of Medicine, David Geffen School of Medicine at UCLA, Los Angeles, California.
Joseph P Lynch IiiDivision of Pulmonary and Critical Care Medicine, Department of Medicine, David Geffen School of Medicine at UCLA, Los Angeles, California.
Michael C FishbeinDepartment of Pathology, David Geffen School of Medicine at UCLA, Los Angeles, California.
Charles McGrawDepartment of Radiological Sciences, UCLA Medical Center, Los Angeles, California.
Jared OyamaDivision of Cardiology, Department of Medicine, David Geffen School of Medicine at UCLA, Los Angeles, California.
John A BelperioDivision of Pulmonary and Critical Care Medicine, Department of Medicine, David Geffen School of Medicine at UCLA, Los Angeles, California.
Rajan SaggarDivision of Pulmonary and Critical Care Medicine, Department of Medicine, David Geffen School of Medicine at UCLA, Los Angeles, California.
University of California, Los Angeles · USUCLA Medical Center · US

Funding

UCLA Clinical and Translational Science InstituteUL1TR000124 · NCATS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI DUBINETT, STEVEN M. · 2012 to 2015
$57.0M
NCATS NIH HHS UL1 TR000124
6 · The paper itself

Abstract

Pulmonary hypertension (PH) is a significant complication of sarcoidosis, occurring in approximately 6 to > 20% of cases, and markedly increases mortality among these patients. The clinician should exercise a high index of suspicion for sarcoidosis-associated PH (SAPH) given the nonspecific symptomatology and the limitations of echocardiography in this patient population. The pathophysiology of PH in sarcoidosis is complex and multifactorial. Importantly, there are inherent differences in the pathogenesis of SAPH compared with idiopathic pulmonary arterial hypertension, making the optimal management of SAPH controversial. In this article, we review the epidemiology, diagnosis, prognosis, and treatment considerations for SAPH. Lung transplantation (LT) is a viable therapeutic option for sarcoid patients with severe pulmonary fibrocystic sarcoidosis or SAPH refractory to medical therapy. We discuss the role for LT in patients with sarcoidosis, review the global experience with LT in this population, and discuss indications and contraindications to LT.

Indexed as

Lung TransplantationEchocardiographyHumansHypertension, PulmonaryPrognosisSarcoidosisSarcoidosis, Pulmonary

Identifiers

PMID25007088
PMCPMC6507426
OpenAlexW2330506633

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.