Evidence map›Paper›PMID 25006878›Full record

ArticlePloS one2014

Epidemic surveillance using an electronic medical record: an empiric approach to performance improvement.

Hongzhang Zheng, Holly Gaff, Gary Smith, Sylvain DeLisle

Abstract read
In one paragraph

Article in PloS one, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Article
  5. Article
  6. Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Hongzhang ZhengVeterans Affairs Maryland Health Care System, Baltimore, Maryland, United States of America; School of Medicine, University of Maryland, Baltimore, Maryland, United States of America.
Holly GaffDepartment of Biological Sciences, Old Dominion University, Norfolk, Virginia, United States of America.
Gary SmithSchool of Veterinary Medicine, University of Pennsylvania, Kennett Square, Pennsylvania, United States of America.
Sylvain DeLisleVeterans Affairs Maryland Health Care System, Baltimore, Maryland, United States of America; School of Medicine, University of Maryland, Baltimore, Maryland, United States of America.

Funding

Developing a Bioterrorism Syndromic Surveillance SystemR01CI000098 · CI · JOHNS HOPKINS UNIVERSITY · PI PERL, TRISH M · 2003 to 2005
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NCPDCID CDC HHS R01 CI000098PHITPO CDC HHS 5U38HK000013-02PHITPO CDC HHS U38 HK000013
6 · The paper itself

Abstract

backgroundsElectronic medical records (EMR) form a rich repository of information that could benefit public health. We asked how structured and free-text narrative EMR data should be combined to improve epidemic surveillance for acute respiratory infections (ARI).

methodsEight previously characterized ARI case detection algorithms (CDA) were applied to historical EMR entries to create authentic time series of daily ARI case counts (background). An epidemic model simulated influenza cases (injection). From the time of the injection, cluster-detection statistics were applied daily on paired background+injection (combined) and background-only time series. This cycle was then repeated with the injection shifted to each week of the evaluation year. We computed: a) the time from injection to the first statistical alarm uniquely found in the combined dataset (Detection Delay); b) how often alarms originated in the background-only dataset (false-alarm rate, or FAR); and c) the number of cases found within these false alarms (Caseload). For each CDA, we plotted the Detection Delay as a function of FAR or Caseload, over a broad range of alarm thresholds.

resultsCDAs that combined text analyses seeking ARI symptoms in clinical notes with provider-assigned diagnostic codes in order to maximize the precision rather than the sensitivity of case-detection lowered Detection Delay at any given FAR or Caseload.

conclusionAn empiric approach can guide the integration of EMR data into case-detection methods that improve both the timeliness and efficiency of epidemic detection.

Indexed as

EpidemicsEpidemiological MonitoringAcute DiseaseArea Under CurveComputer SimulationElectronic Health RecordsHumansInfluenza, HumanMarylandModels, BiologicalQuality ImprovementROC Curve

Identifiers

PMID25006878
PMCPMC4090236

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.