ArticleJournal of neural transmission (Vienna, Austria : 1996)2014
Bacterial melanin increases electrical activity of neurons in Substantia Nigra pars compacta.
Article in Journal of neural transmission (Vienna, Austria : 1996), 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
6 citing papers in PubMed, 13 citations in OpenAlex.
- Postoperative rehabilitation strategies and facial nerve recovery after cerebellopontine angle tumor surgery.European journal of translational myology · 2026Article
- Concentration-dependent effects of bacterial melanin on new superoxide-producing associates in rat tissues: a rotenone neurotoxic model of parkinson's disease.BMC pharmacology & toxicology · 2025Article
- Article
- Melanin biopolymers from microbial world with future perspectives-a review.Archives of microbiology · 2023Review
- Natural Melanin: Current Trends, and Future Approaches, with Especial Reference to Microbial Source.Polymers · 2022Review
- Bacterial melanin crosses the blood-brain barrier in rat experimental model.Fluids and barriers of the CNS · 2014Article
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Bacterial melanin (BM) has been used in different series of experiments as a neuroprotector. It facilitates recovery and regeneration processes after CNS lesions. The action of BM after Substantia Nigra destruction is of major interest. Electrophysiological study tries to reveal the effects of this substance on the electrical activity of Substantia Nigra pars compacta (SNc) neurons. The substance significantly increases the firing rate of SN cdopaminergic neurons. BM increases the rate of excitatory responses after high frequency tetanic stimulation of ipsilateral caudate–putamen. Overall increase in firing rate of SN neurons can contribute to recovery processes after neuronal degeneration in SN.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.