ArticleISRN AIDS2014
Factors Determining Survival and Retention among HIV-Infected Children and Adolescents in a Community Home-Based Care and a Facility-Based Family-Centred Approach in Kampala, Uganda: A Cohort Study.
Article in ISRN AIDS, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 2 of them syntheses that pooled it.
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Who cites it
26 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- HIV-related mortality time trends among children and young adolescents on antiretroviral therapy by age, treatment duration, and region: a systematic review and meta-regression analysis.The lancet. HIV · 2025Pooled it
- Pooled it
- Trial
- Family-Centred Care for Children and Adolescents Living With HIV in Sub-Saharan Africa: A Scoping Review.Journal of the International AIDS Society · 2026Article
- Bayesian meta-analysis of the effectiveness of implementation science evidence in improving health outcomes for adolescent patients accessing ART in sub-Saharan Africa.Frontiers in epidemiology · 2025Review
- Incidence and predictors of attrition among human immunodeficiency virus infected children on antiretroviral therapy in Amhara comprehensive specialized hospitals, Northwest Ethiopia, 2022: a retrospective cohort study.Scientific reports · 2024Article
- Observational
- Survival and predictors of mortality among HIV-positive children on antiretroviral therapy in public hospitals.Journal of pharmaceutical policy and practice · 2022Article
- Incidence and predictors of attrition among children on antiretroviral therapy at University of Gondar Comprehensive Specialized Hospital, Northwest Ethiopia, 2019: Retrospective follow-up study.SAGE open medicine · 2022Article
- Factors associated with viral suppression among adolescents on antiretroviral therapy in Free State province, South Africa.Southern African journal of HIV medicine · 2022Article
- Transitioning from pediatric to adult care and the HIV care continuum in Ghana: a retrospective study.BMC health services research · 2021Article
- A 17 year experience of attrition from care among HIV infected children in Nnewi South-East Nigeria.BMC infectious diseases · 2021Article
- Incidence and predictors of attrition among children attending antiretroviral follow-up in public hospitals, Southern Ethiopia, 2020: a retrospective study.BMJ paediatrics open · 2021Article
- Incidence and Predictors of Loss to Follow-Up Among Children Attending ART Clinics in Northeast Ethiopia: A Retrospective Cohort Study.HIV/AIDS (Auckland, N.Z.) · 2021Article
- Recruitment of Youth Living With HIV to Optimize Adherence and Virologic Suppression: Testing the Design of Technology-Based Community Health Nursing to Improve Antiretroviral Therapy (ART) Clinical Trials.JMIR research protocols · 2020Article
- Discordant retention of HIV-infected mothers and children: Evidence for a family-based approach from Southern Mozambique.Medicine · 2020Observational
- Incidence of Loss to Follow-Up and Its Predictors Among Children with HIV on Antiretroviral Therapy at the University of Gondar Comprehensive Specialized Referral Hospital: A Retrospective Data Analysis.HIV/AIDS (Auckland, N.Z.) · 2020Article
- Retention of HIV exposed infants in care at Arua regional referral hospital, Uganda: a retrospective cohort study.BMC public health · 2019Article
- Predictors of loss to follow-up among children attending HIV clinic in a hospital in rural Kenya.The Pan African medical journal · 2019Article
- Loss to follow-up among children in pre-ART care under the National AIDS Programme, Tamil Nadu, South India.Public health action · 2017Article
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Authors and funding
19 authors.
Funding
Abstract
We describe factors determining retention and survival among HIV-infected children and adolescents engaged in two health care delivery models in Kampala, Uganda: one is a community home-based care (CHBC) and the other is a facility-based family-centred approach (FBFCA). This retrospective cohort study reviewed records from children aged from 0 to 18 years engaged in the two models from 2003 to 2010 focussing on retention/loss to follow-up, mortality, use of antiretroviral therapy (ART), and clinical characteristics. Kaplan Meier survival curves with log rank tests were used to describe and compare retention and survival. Overall, 1,623 children were included, 90.0% (1460/1623) from the CHBC. Children completed an average of 4.2 years of follow-up (maximum 7.7 years). Median age was 53 (IQR: 11-109) months at enrolment. In the CHBC, retention differed significantly between patients on ART and those not (log-rank test, adjusted, P < 0.001). Comparing ART patients in both models, there was no significant difference in long-term survival (log-rank test, P = 0.308, adjusted, P = 0.489), while retention was higher in the CHBC: 94.8% versus 84.7% in the FBFCA (log-rank test, P < 0.001, adjusted P = 0.006). Irrespective of model of care, children receiving ART had better retention in care and survival.
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