Evidence map›Paper›PMID 25006484›Full record

ArticleISRN obstetrics and gynecology2014

Can platelet indices be new biomarkers for severe endometriosis?

Sümeyra Nergiz Avcioğlu, Sündüz Özlem Altinkaya, Mert Küçük, Selda Demircan-Sezer, Hasan Yüksel

Abstract read
In one paragraph

Article in ISRN obstetrics and gynecology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Blood biomarkers for the non-invasive diagnosis of endometriosis.The Cochrane database of systematic reviews · 2016
    Pooled it
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Changes in platelet parameters in leukocytosis.The Pan African medical journal · 2016
    Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Sümeyra Nergiz AvcioğluDepartment of Gynecology and Obstetrics, Adnan Menderes University, School of Medicine, 09100 Aydın, Turkey.
Sündüz Özlem AltinkayaDepartment of Gynecology and Obstetrics, Adnan Menderes University, School of Medicine, 09100 Aydın, Turkey.
Mert KüçükDepartment of Gynecology and Obstetrics, Muğla Sıtkı Koçman University, School of Medicine, 48000 Muğla, Turkey.
Selda Demircan-SezerDepartment of Gynecology and Obstetrics, Adnan Menderes University, School of Medicine, 09100 Aydın, Turkey.
Hasan YükselDepartment of Gynecology and Obstetrics, Adnan Menderes University, School of Medicine, 09100 Aydın, Turkey.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective. The aim of this study was to investigate whether platelet indices-mean platelet volume (MPV), platelet distribution width (PDW), and plateletcrit (PCT) would be useful as noninvasive biomarkers for determining the severity of endometriosis. Methods. A retrospective review of the medical charts of 164 patients diagnosed with endometriosis and who were operated on between 2001 and 2013 was performed. The stage of endometriosis was determined according to revised American Society for Reproductive Medicine criteria. Results. In patients with advanced endometriosis (Stages 3-4), PLT, PCT levels were found to be significantly higher and MPV, PDW values to be significantly lower when compared to initial endometriosis (Stages 1-2). In addition, there was a significant positive correlation between PLT (r: 0.800, P: 0.001) and PCT (r: 0.727, P: 0.002) and the inflammatory marker white blood cell count (WBC). Conclusion. Our finding may not sufficient for employing platelet indices solely in this differential diagnosis, but our finding could provide a suggestion for clinical physicians so that attention is paid to the value of platelet indices and that these may be taken into account when making decisions about the initial or advanced stages of endometriosis.

Identifiers

PMID25006484
PMCPMC4076665

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.