Evidence map›Paper›PMID 25006192›Full record

SynthesisJournal of the National Cancer Institute2014

Recommended patient-reported core set of symptoms to measure in prostate cancer treatment trials.

Ronald C Chen, Peter Chang, Richard J Vetter, Himansu Lukka, William A Stokes, Martin G Sanda, Deborah Watkins-Bruner, Bryce B Reeve, Howard M Sandler

Abstract readConsensus Development Conference, NIHSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Journal of the National Cancer Institute, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 49 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
49citing papers in PubMed, 5 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

49 citing papers in PubMed, 5 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Guideline
  5. Pooled it
  6. Trial
  7. Trial
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  12. Article
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  15. Review
  16. Salvage Reirradiation for Locally Recurrent Prostate Cancer: Results From a Prospective Study With 7.2 Years of Follow-Up.Journal of clinical oncology : official journal of the American Society of Clinical Oncology · 2024
    Article
  17. Article
  18. Article
  19. Article
  20. Reliability and validity of PRO-CTCAE® daily reporting with a 24-hour recall period.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2023
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors.

Ronald C ChenAffiliations of authors: Department of Radiation Oncology (RCC, WAS), and Department of Health Policy and Management, Gillings School of Global Public Health (BBR), Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, NC (RCC, WAS); Division of Urology, Department of Surgery, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA (PC); Mayo Clinic, Rochester, MN (RJV); Juravinski Cancer Centre and McMaster University, Hamilton, Ontario, Canada (HL); Department of Urology (MGS), and Nell Hodgson Woodruff School of Nursing (DW-G), Emory University, Atlanta, GA; Department of Radiation Oncology, Cedars Sinai Medical Center, Los Angeles, CA (HMS). ronald_chen@med.unc.edu.
Peter ChangAffiliations of authors: Department of Radiation Oncology (RCC, WAS), and Department of Health Policy and Management, Gillings School of Global Public Health (BBR), Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, NC (RCC, WAS); Division of Urology, Department of Surgery, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA (PC); Mayo Clinic, Rochester, MN (RJV); Juravinski Cancer Centre and McMaster University, Hamilton, Ontario, Canada (HL); Department of Urology (MGS), and Nell Hodgson Woodruff School of Nursing (DW-G), Emory University, Atlanta, GA; Department of Radiation Oncology, Cedars Sinai Medical Center, Los Angeles, CA (HMS).
Richard J VetterAffiliations of authors: Department of Radiation Oncology (RCC, WAS), and Department of Health Policy and Management, Gillings School of Global Public Health (BBR), Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, NC (RCC, WAS); Division of Urology, Department of Surgery, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA (PC); Mayo Clinic, Rochester, MN (RJV); Juravinski Cancer Centre and McMaster University, Hamilton, Ontario, Canada (HL); Department of Urology (MGS), and Nell Hodgson Woodruff School of Nursing (DW-G), Emory University, Atlanta, GA; Department of Radiation Oncology, Cedars Sinai Medical Center, Los Angeles, CA (HMS).
Himansu LukkaAffiliations of authors: Department of Radiation Oncology (RCC, WAS), and Department of Health Policy and Management, Gillings School of Global Public Health (BBR), Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, NC (RCC, WAS); Division of Urology, Department of Surgery, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA (PC); Mayo Clinic, Rochester, MN (RJV); Juravinski Cancer Centre and McMaster University, Hamilton, Ontario, Canada (HL); Department of Urology (MGS), and Nell Hodgson Woodruff School of Nursing (DW-G), Emory University, Atlanta, GA; Department of Radiation Oncology, Cedars Sinai Medical Center, Los Angeles, CA (HMS).
William A StokesAffiliations of authors: Department of Radiation Oncology (RCC, WAS), and Department of Health Policy and Management, Gillings School of Global Public Health (BBR), Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, NC (RCC, WAS); Division of Urology, Department of Surgery, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA (PC); Mayo Clinic, Rochester, MN (RJV); Juravinski Cancer Centre and McMaster University, Hamilton, Ontario, Canada (HL); Department of Urology (MGS), and Nell Hodgson Woodruff School of Nursing (DW-G), Emory University, Atlanta, GA; Department of Radiation Oncology, Cedars Sinai Medical Center, Los Angeles, CA (HMS).
Martin G SandaAffiliations of authors: Department of Radiation Oncology (RCC, WAS), and Department of Health Policy and Management, Gillings School of Global Public Health (BBR), Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, NC (RCC, WAS); Division of Urology, Department of Surgery, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA (PC); Mayo Clinic, Rochester, MN (RJV); Juravinski Cancer Centre and McMaster University, Hamilton, Ontario, Canada (HL); Department of Urology (MGS), and Nell Hodgson Woodruff School of Nursing (DW-G), Emory University, Atlanta, GA; Department of Radiation Oncology, Cedars Sinai Medical Center, Los Angeles, CA (HMS).
Deborah Watkins-BrunerAffiliations of authors: Department of Radiation Oncology (RCC, WAS), and Department of Health Policy and Management, Gillings School of Global Public Health (BBR), Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, NC (RCC, WAS); Division of Urology, Department of Surgery, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA (PC); Mayo Clinic, Rochester, MN (RJV); Juravinski Cancer Centre and McMaster University, Hamilton, Ontario, Canada (HL); Department of Urology (MGS), and Nell Hodgson Woodruff School of Nursing (DW-G), Emory University, Atlanta, GA; Department of Radiation Oncology, Cedars Sinai Medical Center, Los Angeles, CA (HMS).
Bryce B ReeveAffiliations of authors: Department of Radiation Oncology (RCC, WAS), and Department of Health Policy and Management, Gillings School of Global Public Health (BBR), Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, NC (RCC, WAS); Division of Urology, Department of Surgery, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA (PC); Mayo Clinic, Rochester, MN (RJV); Juravinski Cancer Centre and McMaster University, Hamilton, Ontario, Canada (HL); Department of Urology (MGS), and Nell Hodgson Woodruff School of Nursing (DW-G), Emory University, Atlanta, GA; Department of Radiation Oncology, Cedars Sinai Medical Center, Los Angeles, CA (HMS).
Howard M SandlerAffiliations of authors: Department of Radiation Oncology (RCC, WAS), and Department of Health Policy and Management, Gillings School of Global Public Health (BBR), Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, NC (RCC, WAS); Division of Urology, Department of Surgery, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA (PC); Mayo Clinic, Rochester, MN (RJV); Juravinski Cancer Centre and McMaster University, Hamilton, Ontario, Canada (HL); Department of Urology (MGS), and Nell Hodgson Woodruff School of Nursing (DW-G), Emory University, Atlanta, GA; Department of Radiation Oncology, Cedars Sinai Medical Center, Los Angeles, CA (HMS).

Funding

Virology Research Program (Program 4)P30CA016086 · NCI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Deborah F. Tate · 1985 to 2026
$201.5M
NCI NIH HHS P30 CA016086
6 · The paper itself

Abstract

The National Cancer Institute (NCI) Symptom Management and Health-Related Quality of Life Steering Committee convened four working groups to recommend core sets of patient-reported outcomes to be routinely incorporated in clinical trials. The Prostate Cancer Working Group included physicians, researchers, and a patient advocate. The group's process included 1) a systematic literature review to determine the prevalence and severity of symptoms, 2) a multistakeholder meeting sponsored by the NCI to review the evidence and build consensus, and 3) a postmeeting expert panel synthesis of findings to finalize recommendations. Five domains were recommended for localized prostate cancer: urinary incontinence, urinary obstruction and irritation, bowel-related symptoms, sexual dysfunction, and hormonal symptoms. Four domains were recommended for advanced prostate cancer: pain, fatigue, mental well-being, and physical well-being. Additional domains for consideration include decisional regret, satisfaction with care, and anxiety related to prostate cancer. These recommendations have been endorsed by the NCI for implementation.

Indexed as

Quality of LifeSelf ReportAnxietyClinical Trials as TopicDecision MakingErectile DysfunctionFatigueHealth StatusHumansIntestine, LargeMaleNational Cancer Institute (U.S.)Patient SatisfactionProstatic NeoplasmsSeverity of Illness IndexSurveys and Questionnaires

Identifiers

PMID25006192
PMCPMC4192044

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.