Evidence map›Paper›PMID 25005910›Full record

ArticlePediatric surgery international2014

Colorectal carcinoma in first decade of life: our experience.

M A Mushfiqur Rahman, Tanvir K Chowdhury, Md Akbar Husain Bhuiyan, Md Abdullah Al Farooq, Md Minhajuddin Sajid, Tahmina Banu

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Article in Pediatric surgery international, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Pediatric Colorectal Carcinoma: A Series of Seven Cases.Journal of Indian Association of Pediatric Surgeons
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

M A Mushfiqur RahmanDepartment of Pediatric Surgery, Chittagong Medical College and Hospital, Chittagong, Bangladesh.
Tanvir K Chowdhury
Md Akbar Husain Bhuiyan
Md Abdullah Al Farooq
Md Minhajuddin Sajid
Tahmina Banu

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThough the lifetime risk of colorectal carcinoma (CRC) in general population is 5-6 %, it is uncommon in pediatric age group. Here, we are reporting our experience of CRC in the first decade of life.

methodsFrom January 2010 to December 2013, seven patients with histopathologically confirmed colorectal carcinoma were treated in the Department of Pediatric Surgery, Chittagong Medical College and hospital. Age, sex, presenting symptoms, location of the primary tumor, serum CEA level, treatment modalities and outcomes were evaluated.

resultsThere were four male and three female patients and age ranged from 6.5 to 10.5 years. Rectum (3 patients) and rectosigmoid (2 patients) were the most common primary sites. Serum carcinoembryonic antigen level was obtained in six patients and in only one patient the level was raised markedly (137 ng/ml). Two patients of familial adenomatous polyposis had localized disease and others presented in an advanced stage. Histopathologically, poorly differentiated adenocarcinoma was noted in five patients with one signet ring cell type and well differentiated in rest of the two patients. Only one patient was surviving at the last follow up.

conclusionAdvanced stage at diagnosis, aggressive histologic subtype and poor survival are the hallmarks of pediatric CRC.

Indexed as

AdenocarcinomaAdolescentBangladeshBiomarkers, TumorCarcinoembryonic AntigenChildColorectal NeoplasmsFemaleFollow-Up StudiesHumansIncidenceMalePrognosisRectumRetrospective StudiesSurvival RateBiomarkers, TumorCarcinoembryonic Antigen

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.