Evidence map›Paper›PMID 25005812›Full record

Trial reportObesity surgery2015

Argon plasma coagulation of gastrojejunal anastomosis for weight regain after gastric bypass.

Giorgio A P Baretta, Helga C A W Alhinho, Jorge Eduardo F Matias, João Batista Marchesini, João Henrique F de Lima, Celso Empinotti, Josemberg M Campos

2 registry-linked trialsAbstract readClinical Trial
PubMed Publisher
In one paragraph

Trial report in Obesity surgery, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 33 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed, 3 pooled it
5.6field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03264027 nacompletednot on this mapstarted 2017, after this paper: background citation

A Multicenter Randomized Clinical Trial of Carbon Dioxide (CO2) Versus Air Insufflation for the Application of Argon Plasma to Reduce the Gastrojejunal Anastomosis in Individuals With Weight Regain After Bypass Surgery.

TypeinterventionalSponsorKaiser Clinic and HospitalRan2017 to 2020Enrolled200ConditionsDilatation of Anastomosis, Bypass Complication, ObesityArmsCarbon dioxide, Ambient air, Argon fulguration
NCT05870943 naunknown statusnot on this mapstarted 2023, after this paper: background citation

Hybrid Argon Plasma Coagulation and Endoscopic Sleeve Gastroplasty Trial: A Single-Center Randomized Controlled Validation Trial in a Community Setting

TypeinterventionalSponsorTrue You Weight LossRan2023 to 2025Enrolled48ConditionsObesityArmsHybrid Argon Plasma Coagulation, Endoscopic Sleeve Gastroplasty
3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 3 syntheses or guidelines pooled it, 93 citations in OpenAlex.

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  18. Endoscopic therapy of weight regain after bariatric surgery.World journal of gastrointestinal surgery · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Giorgio A P BarettaUniversidade Federal do Paraná, 1375 Alameda Presidente Taunay, 80430-000, Curitiba, PR, Brazil, giorgio.baretta@gmail.com.
Helga C A W Alhinho
Jorge Eduardo F Matias
João Batista Marchesini
João Henrique F de Lima
Celso Empinotti
Josemberg M Campos
Universidade Federal do Paraná · BRUniversidade Federal de Pernambuco · BRUniversidade Federal de Santa Catarina · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe failure of approximately 20 % of obese patients who undergo Roux-en-Y gastric bypass (RYGB) to maintain weight loss over the following 18-24 months is related to the surgical procedure, to the patient, or both. Although the underlying mechanisms are uncertain, one factor that has been postulated is the dilation of the gastrojejunal anastomosis. The objective was to evaluate the safety and efficacy of the serial use of argon plasma coagulation (APC) in reducing the diameter of the dilated gastrojejunal anastomosis and post-RYGB weight regain.

methodsWe carried out a prospective, nonrandomized study of 30 patients, with no control or sham group, monitoring RYGB weight regain associated with dilation of the gastrojejunal anastomosis over a postoperative period of 18 months. Each patient underwent three sessions of APC in the anastomosis separated by 8 weeks, with a final endoscopic examination 8 weeks after the last session.

resultsThere was a loss of 15.48 kg (range = 8.0-16.0 kg) of the 19.6 kg (range = 7.0-39.0 kg) of regained weight after RYGB and a reduction of 66.89 % in the final anastomotic diameter, with statistically significant reductions between each APC session. Previous body mass index significantly decreased up to the final examination, and the final weight was close to but not at the same level as the nadir.

conclusionsOur study indicates that the use of APC to treat weight regain after RYGB is a safe and effective procedure and promotes a reduction in gastrojejunal anastomosis, final weight, and BMI, with a low rate of complications.

Indexed as

Argon Plasma CoagulationWeight GainAdultAnastomosis, Roux-en-YBody Mass IndexDilatation, PathologicEndoscopyFemaleGastric BypassHumansJejunumMaleMiddle AgedObesity, MorbidReoperationTreatment Failure

Identifiers

PMID25005812
OpenAlexW2071921871

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.