Evidence map›Paper›PMID 25005693›Full record

ArticleBioTechniques2014

Multi-modality imaging of a murine mammary window chamber for breast cancer research.

Rachel Schafer, Hui Min Leung, Arthur F Gmitro

Open access · goldAbstract read
In one paragraph

Article in BioTechniques, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 26 citations in OpenAlex.

  1. Review
  2. Review
  3. Applications of Intravital Imaging in Cancer Immunotherapy.Bioengineering (Basel, Switzerland) · 2024
    Review
  4. Review
  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Review of quantitative multiscale imaging of breast cancer.Journal of medical imaging (Bellingham, Wash.) · 2018
    Review
  11. Review
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Rachel SchaferDepartment of Biomedical Engineering, University of Arizona, Tucson, AZ.
Hui Min LeungCollege of Optical Sciences, University of Arizona, Tucson, AZ; Department of Medical Imaging, University of Arizona, Tucson, AZ.
Arthur F GmitroCollege of Optical Sciences, University of Arizona, Tucson, AZ; Department of Medical Imaging, University of Arizona, Tucson, AZ.
Banner - University Medical Center Tucson · USUniversity of Arizona · US

Funding

Graduate Training in Biomedical Imaging SpectrocopyT32EB000809 · NIBIB · UNIVERSITY OF ARIZONA · PI GMITRO, ARTHUR F. · 2003 to 2018
$3.3M
NIBIB NIH HHS T32 EB000809NIBIB NIH HHS T32EB000809
6 · The paper itself

Abstract

Window chamber models have been developed and utilized as a means to study the complex microenvironment in which cancers develop, proliferate, and metastasize in small animals. Here we utilize rapid prototyping printer technology to construct a new plastic orthotopic mammary window chamber that is compatible with magnetic resonance imaging, nuclear imaging, and optical imaging. Optical imaging allows for high-resolution cellular and molecular level analysis of tissues; magnetic resonance imaging provides quantitative measures of tumor size, perfusion, diffusion, fat/water content relaxation parameters; and a nuclear imaging technique, called the Beta Imager, supports functional and metabolic imaging. Our demonstration of the multiple imaging capabilities of this model suggests that it can be used as a powerful platform for studying basic cancer biology and developing new cancer therapies.

Indexed as

AnimalsBreast NeoplasmsCell Line, TumorEquipment DesignFemaleHumansImage Processing, Computer-AssistedMagnetic Resonance ImagingMammary Glands, AnimalMice, SCIDMicroscopy, ConfocalMultimodal Imagingcancerimagingmagnetic resonancenuclearopticalwindow chamber

Identifiers

PMID25005693
PMCPMC4136411
OpenAlexW2206071427

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.